Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEDUGWF)
| DME Name | Inositol dehydrogenase (idh) | ||||
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| Synonyms | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; MI 2-dehydrogenase/DCI 3-dehydrogenase; iolG | ||||
| Gene Name | iolG | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| 3D Structure | |||||
| EC Number | EC: 1.1.1.18 | ||||
| Lineage | Species: Lactobacillus casei | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MVVKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTS
LLQDPDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLATTLEGAKRIVDKELTKSKKV IQVGFMRRYDQGIRALKEKLDTGIIGAPLVVRASHINPNVASNYSNEMAITDTLIHEIDE MHWLLDDEYTSIQITYPRQSAEVRNEGLHDPQLATLTTKKGTVIQVLVHVTAQYGYEVKL EVIGETGELQLPNYGLGPILRSNANQQTAVEMSWINRFIQAYNTEVQEFIDQVAKSEPPV GPSAWDGYIAAITAAAANRSQKDQETVLINVAGTPTFYQNKNAIHA |
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| Function | This enzyme involves in the oxidation of myo-inositol and D-chiro-inositol to 2-keto-myo-inositol and 1-keto-D-chiro-inositol, respectively. | ||||
Molecular Interaction Atlas (MIA) of This DME
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1 Clinical Trial Drug(s) Metabolized by This DME
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