Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEMW0RC)
| DME Name | Azoreductase (azoR) | ||||
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| Synonyms | Azo-dye reductase; FMN-dependent NADH-azo compound oxidoreductase; FMN-dependent NADH-azoreductase; azoR; JW1409; acpD; b1412 | ||||
| Gene Name | azoR | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| 3D Structure | |||||
| Gene ID | |||||
| EC Number | EC: 1.7.1.6 | ||||
| Lineage | Species: Fusobacterium nucleatum | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALR
PSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFR YTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYG PEMAAKAQSDAKAAIDSIVSA |
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| Function | This enzyme catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. | ||||
Molecular Interaction Atlas (MIA) of This DME
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1 Clinical Trial Drug(s) Metabolized by This DME
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