Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEWTCUK)
| DME Name | Beta-glucuronidase (uidA) | ||||
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| Synonyms | Beta-galactosidase/beta-glucuronidase; Beta-galactosidase BgaB; gusA | ||||
| Gene Name | gusA | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 3.2.1.31 | ||||
| Lineage | Species: Lactobacillus gasseri | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MESALYPIQNKYRFNTLMNGTWQFETDPNSVGLDEGWNKELPDPEEMPVPGTFAELTTKR
DRKYYTGDFWYQKDFFIPSFLKKKELYIRFGSVTHRAKVFINGHEVGQHEGGFLPFQVKI SNYINYDQTNRVTVLVNNELSEKAIPCGTEEILDNGQKLAQPYFDFFNYSGIMRNVWLLA LPQSQITNFKLNYQLANNKATITYNIEANNNAEFKVTLFDNQKEVACATSKNTSSLTIKN PHLWSPNDPYSYKIKIEMLEDGKTVDEYTDKIGIRTVKIVNDKILLNNHPIYLKGFGKHE DFNVLGKAVNESIIKRDYECMKWIGANCFRSSHYPYAEEWYQYADKYGFLIIDEVPAVGL NRSITNFLNVTNSNQSHFFASKTVPELKKVHEQEIKEMIDRDQRHPSVIAWSLFNEPEST TQESYDYFKDIFAFARKLDPQNRPYTGTLVMGSGPKVDKLHPLCDFVCLNRYYGWYVAGG PEIVNAKKMLEDELDGWQNLKLNKPFVFTEFGADTLSSSHRLPDEMWSQEYQNEYYQMYF DIFKKYPFICGELVWNFADFKTSEGIMRVGGNDKGIFTRDREPKDIAFTLKKRWQQLN |
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| Function | This enzyme takes part in glucuronoside catabolic process. It catalyzes the hydrolysis of beta-glucuronide containing substrates. | ||||
Molecular Interaction Atlas (MIA) of This DME
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Approved Drug(s) Metabolized by This DME
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