General Information of Drug Off-Target (DOT) (ID: OT0BQQU9)

DOT Name Putative cyclin-dependent kinase inhibitor 1A (cdkn1a)
Synonyms P21/WAF1/CIP1
Gene Name cdkn1a
UniProt ID
Q683K8_CANLF
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Pfam ID
PF02234
Sequence
DCDALMASCVQEARERWNFDFVTETPLEGDFAWERVRGLGLSKVSLPAGPRGGRDDLGGG
KRPGTSPALLQGTAQEDHLDLSLTCTLLPHSPERPEASPGVPGTSQGRKRRQTSMTDFYH
SKRRLIFSKRKP

Molecular Interaction Atlas (MIA) of This DOT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DOT
This DOT Affected the Drug Response of 1 Drug(s)
Drug Name Drug ID Highest Status Interaction REF
Cidofovir DMA13GD Approved Putative cyclin-dependent kinase inhibitor 1A (cdkn1a) increases the Apoptosis ADR of Cidofovir. [1]
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References

1 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.