Details of Drug Off-Target (DOT)

General Information of Drug Off-Target (DOT) (ID: OTZ84GNP)

DOT Name	HLA-DR3 (HLA-DRB1)
Gene Name	HLA-DRB1
UniProt ID	Q29887_HUMAN
Pfam ID	PF00969
Sequence	YSTSEXHFFNGTERVRYLDRYFHNQEENVRFDSDVGEFRAVTELGRPDXEYWNXQKDLLE QKRGRVDTYCRHNYGVGESFT

Molecular Interaction Atlas (MIA) of This DOT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DOT

This DOT Affected the Drug Response of 1 Drug(s)

Drug Name	Drug ID	Highest Status	Interaction	REF
Penicillamine	DM40EF6	Approved	HLA-DR3 (HLA-DRB1) increases the Drug toxicity ADR of Penicillamine.	[1]
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References

1	ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.