DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Myc proto-oncogene protein (MYC)
|
OTPV5LUK
|
MYC_HUMAN
|
Decreases Expression
|
[6] |
Cellular tumor antigen p53 (TP53)
|
OTIE1VH3
|
P53_HUMAN
|
Increases Activity
|
[7] |
Zinc finger protein GLI1 (GLI1)
|
OT1BTAJO
|
GLI1_HUMAN
|
Decreases Expression
|
[6] |
Poly polymerase 1 (PARP1)
|
OT310QSG
|
PARP1_HUMAN
|
Increases Cleavage
|
[8] |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1)
|
OTSBQR6D
|
PLCG1_HUMAN
|
Decreases Phosphorylation
|
[9] |
G1/S-specific cyclin-D1 (CCND1)
|
OT8HPTKJ
|
CCND1_HUMAN
|
Decreases Expression
|
[6] |
Mitogen-activated protein kinase 3 (MAPK3)
|
OTCYKGKO
|
MK03_HUMAN
|
Decreases Phosphorylation
|
[8] |
Mitogen-activated protein kinase 1 (MAPK1)
|
OTH85PI5
|
MK01_HUMAN
|
Decreases Phosphorylation
|
[8] |
Catenin beta-1 (CTNNB1)
|
OTZ932A3
|
CTNB1_HUMAN
|
Decreases Expression
|
[6] |
Vascular endothelial growth factor receptor 2 (KDR)
|
OT15797V
|
VGFR2_HUMAN
|
Decreases Phosphorylation
|
[9] |
Cyclin-dependent kinase inhibitor 1 (CDKN1A)
|
OTQWHCZE
|
CDN1A_HUMAN
|
Decreases Expression
|
[10] |
Caspase-3 (CASP3)
|
OTIJRBE7
|
CASP3_HUMAN
|
Increases Activity
|
[6] |
Casein kinase I isoform alpha (CSNK1A1)
|
OTJ6O1IC
|
KC1A_HUMAN
|
Increases Expression
|
[6] |
Glycogen synthase kinase-3 beta (GSK3B)
|
OTL3L14B
|
GSK3B_HUMAN
|
Increases Expression
|
[6] |
Caspase-9 (CASP9)
|
OTD4RFFG
|
CASP9_HUMAN
|
Increases Cleavage
|
[8] |
Focal adhesion kinase 1 (PTK2)
|
OT3Q1JDY
|
FAK1_HUMAN
|
Decreases Phosphorylation
|
[9] |
Apoptosis regulator BAX (BAX)
|
OTAW0V4V
|
BAX_HUMAN
|
Increases Expression
|
[8] |
Potassium voltage-gated channel subfamily H member 2 (KCNH2)
|
OTZX881H
|
KCNH2_HUMAN
|
Decreases Activity
|
[11] |
Forkhead box protein P3 (FOXP3)
|
OTA9Z9OC
|
FOXP3_HUMAN
|
Increases Expression
|
[8] |
F-box/WD repeat-containing protein 1A (BTRC)
|
OT2EZDGR
|
FBW1A_HUMAN
|
Decreases Expression
|
[8] |
Cytochrome P450 1A1 (CYP1A1)
|
OTE4EFH8
|
CP1A1_HUMAN
|
Increases Metabolism
|
[5] |
ATP-dependent translocase ABCB1 (ABCB1)
|
OTEJROBO
|
MDR1_HUMAN
|
Increases Transport
|
[5] |
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