Molecular Interaction Atlas (MIA) |
|
Indication(s) of Oxyphenbutazone |
Disease Entry |
ICD 11 |
Status |
REF |
Arthritis |
FA20
|
Approved |
[2] |
|
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Oxyphenbutazone Interacts with 1 DTT Molecule(s)
DTT Name |
DTT ID |
UniProt ID |
Mode of Action |
REF |
Serum albumin (ALB)
|
TTFNGC9
|
ALBU_HUMAN
|
Modulator
|
[4] |
------------------------------------------------------------------------------------ |
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Oxyphenbutazone Interacts with 1 DOT Molecule(s)
DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Heat shock factor protein 1 (HSF1)
|
OTYNJ4KP
|
HSF1_HUMAN
|
Increases Activity
|
[5] |
------------------------------------------------------------------------------------ |
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Indication(s) of Maprotiline |
Disease Entry |
ICD 11 |
Status |
REF |
Depression |
6A70-6A7Z
|
Approved |
[3] |
Major depressive disorder |
6A70.3
|
Approved |
[2] |
Mixed anxiety and depressive disorder |
N.A.
|
Investigative |
[3] |
|
|
Maprotiline Interacts with 1 DTT Molecule(s)
DTT Name |
DTT ID |
UniProt ID |
Mode of Action |
REF |
Norepinephrine transporter (NET)
|
TTAWNKZ
|
SC6A2_HUMAN
|
Inhibitor
|
[6] |
------------------------------------------------------------------------------------ |
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Maprotiline Interacts with 2 DME Molecule(s)
DME Name |
DME ID |
UniProt ID |
Mode of Action |
REF |
Cytochrome P450 1A2 (CYP1A2)
|
DEJGDUW
|
CP1A2_HUMAN
|
Metabolism
|
[7] |
Cytochrome P450 2D6 (CYP2D6)
|
DECB0K3
|
CP2D6_HUMAN
|
Metabolism
|
[7] |
------------------------------------------------------------------------------------ |
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|
Maprotiline Interacts with 2 DOT Molecule(s)
DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Cytochrome P450 2D6 (CYP2D6)
|
OTZJC802
|
CP2D6_HUMAN
|
Increases ADR
|
[8] |
Beclin-1 (BECN1)
|
OT4X293M
|
BECN1_HUMAN
|
Increases Expression
|
[9] |
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