DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Telomerase reverse transcriptase (TERT)
|
OT085VVA
|
TERT_HUMAN
|
Decreases Expression
|
[7] |
Baculoviral IAP repeat-containing protein 5 (BIRC5)
|
OTILXZYL
|
BIRC5_HUMAN
|
Decreases Expression
|
[9] |
Forkhead box protein O3 (FOXO3)
|
OTHXQG4P
|
FOXO3_HUMAN
|
Increases Expression
|
[9] |
Poly polymerase 1 (PARP1)
|
OT310QSG
|
PARP1_HUMAN
|
Increases Cleavage
|
[10] |
Apoptosis regulator Bcl-2 (BCL2)
|
OT9DVHC0
|
BCL2_HUMAN
|
Decreases Expression
|
[7] |
Proto-oncogene tyrosine-protein kinase Src (SRC)
|
OTETYX40
|
SRC_HUMAN
|
Increases Phosphorylation
|
[10] |
Mitogen-activated protein kinase 3 (MAPK3)
|
OTCYKGKO
|
MK03_HUMAN
|
Increases Phosphorylation
|
[10] |
Mitogen-activated protein kinase 1 (MAPK1)
|
OTH85PI5
|
MK01_HUMAN
|
Increases Phosphorylation
|
[10] |
Serine/threonine-protein kinase mTOR (MTOR)
|
OTHH8KU7
|
MTOR_HUMAN
|
Increases Phosphorylation
|
[10] |
Caspase-3 (CASP3)
|
OTIJRBE7
|
CASP3_HUMAN
|
Increases Activity
|
[7] |
Mitogen-activated protein kinase 8 (MAPK8)
|
OTEREYS5
|
MK08_HUMAN
|
Increases Phosphorylation
|
[10] |
Small ribosomal subunit protein eS6 (RPS6)
|
OTT4D1LN
|
RS6_HUMAN
|
Decreases Phosphorylation
|
[11] |
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
|
OT2YYI1A
|
MCL1_HUMAN
|
Decreases Expression
|
[7] |
Baculoviral IAP repeat-containing protein 3 (BIRC3)
|
OT3E95KB
|
BIRC3_HUMAN
|
Decreases Expression
|
[7] |
Baculoviral IAP repeat-containing protein 2 (BIRC2)
|
OTFXFREP
|
BIRC2_HUMAN
|
Decreases Expression
|
[7] |
Bcl2-associated agonist of cell death (BAD)
|
OT63ERYM
|
BAD_HUMAN
|
Increases Expression
|
[7] |
NAD-dependent protein deacetylase sirtuin-1 (SIRT1)
|
OTAYZMOY
|
SIR1_HUMAN
|
Decreases Expression
|
[7] |
RAC-alpha serine/threonine-protein kinase (AKT1)
|
OT8H2YY7
|
AKT1_HUMAN
|
Decreases Response To Substance
|
[12] |
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