Details of the Drug Combinations

General Information of This Drug (ID: DM05968)

Drug Name
Otilonium bromide   DM05968
Synonyms
Otilonium Bromide; 26095-59-0; Octylonium bromide; Spasmomen; Octylonium; Otilonium (bromide); SP63; Ottilonio bromuro [Italian]; UNII-21HN3N72PV; Otilonium bromide [INN:BAN]; Otilonii bromidum [INN-Latin]; Bromure d'otilonium [INN-French]; Bromuro de otilonio [INN-Spanish]; EINECS 247-457-4; 21HN3N72PV; Diethyl(2-hydroxyethyl)methylammonium bromide p-(o-(octyloxy)benzamido)benzoate; Ethanaminium, N,N-diethyl-N-methyl-2-((4-((2-(octyloxy)benzoyl)amino)benzoyl)oxy)-, bromide; DSSTox_CID_26357; DSSTox_RID_81559
Indication
Disease Entry ICD 11 Status REF
Gastric motility disorder DA21 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

15 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Lumefantrine + Otilonium bromide DCWAXUA Lumefantrine Hepatoblastoma (Cell Line: HB3) [2]
Otilonium bromide + Lumefantrine DCLR0MA Lumefantrine DD2 (Cell Line: DD2) [2]
Otilonium bromide + Lumefantrine DCWJEI6 Lumefantrine Hepatoblastoma (Cell Line: HB3) [2]
Otilonium bromide + Artemether DC46EBV Artemether Hepatoblastoma (Cell Line: HB3) [2]
Otilonium bromide + Diltiazem DCYRZRF Diltiazem DD2 (Cell Line: DD2) [2]
Otilonium bromide + Diltiazem DC5M76P Diltiazem Hepatoblastoma (Cell Line: HB3) [2]
Otilonium bromide + Idarubicin DCAFJK9 Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Otilonium bromide + Methylene blue DCYRB0F Methylene blue DD2 (Cell Line: DD2) [2]
Otilonium bromide + Artemisinin DCK6YFW Artemisinin DD2 (Cell Line: DD2) [2]
Otilonium bromide + Chloroquine DCQW90E Chloroquine DD2 (Cell Line: DD2) [2]
Otilonium bromide + Chloroquine DC5V6JP Chloroquine Hepatoblastoma (Cell Line: HB3) [2]
Otilonium bromide + Piperaquine DCC18RO Piperaquine Hepatoblastoma (Cell Line: HB3) [2]
Otilonium bromide + Mefloquine DC1JO3F Mefloquine DD2 (Cell Line: DD2) [2]
Otilonium bromide + Mefloquine DC1MFKQ Mefloquine Hepatoblastoma (Cell Line: HB3) [2]
Proguanil + Otilonium bromide DCMCVN5 Proguanil Hepatoblastoma (Cell Line: HB3) [2]
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⏷ Show the Full List of 15 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.