Details of the Drug Combinations

General Information of This Drug (ID: DM0G5O6)

Drug Name

Flumatinib DM0G5O6

Synonyms

HH-GV-678

Indication

Disease Entry	ICD 11	Status	REF
Chronic myelogenous leukaemia	2A20.0	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Flumatinib + Nilotinib	DCB2D5A	Nilotinib	CML-CP; Mutation;Suboptimal Response or Failure in TKI	[2]
Flumatinib + Venetoclax	DCY4KNM	Venetoclax	Philadelphia Chromosome	[3]
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References

1	ClinicalTrials.gov (NCT02511340) A Phase II Study to Evaluate the Efficacy and the Safety of Flumatinib in CML-AP or CML-BP Patients.
2	ClinicalTrials.gov (NCT04681820) Evaluating Efficacy and Safety of Flumatinib for Chronic Phase Chronic Myeloid Leukemia(CML-CP) Without Optimal Response (Warning,Failure) to Imatinib or Dasatinib
3	ClinicalTrials.gov (NCT05433532) Study of AzacitidineVenetoclaxand Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients