Details of the Drug Combinations

General Information of This Drug (ID: DM1DBV5)

Drug Name

Dexlansoprazole DM1DBV5

Synonyms

dexlansoprazole; (R)-Lansoprazole; 138530-94-6; Kapidex; dexilant; R-(+)-LANSOPRAZOLE; Dexilant Solutab; TAK 390; UNII-UYE4T5I70X; TAK-390; (r)-(+)-lansoprazole; T 168390; UYE4T5I70X; AK170558; TAK-390MR; T-168390; 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole; 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methylsulfinyl]-1H-benzimidazole; (R)-2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole; Dexlansoprazole (INN/USAN); Kapidex; KS-1075; Lansoprazole

Indication

Disease Entry	ICD 11	Status	REF
Erosive esophagitis	DA25.0	Approved	[1]
Non-erosive gastro-esophageal reflux disease	DA22.0	Approved	[1]
Peptic ulcer	DA61	Approved	[2]
NSAID-associated gastric ulcer	DA60	Phase 3	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Dexlansoprazole + Clarithromycin	DC8BV1J	Clarithromycin	Helicobacter Pylori Infection	[3]
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References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 022287.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7208).
3	ClinicalTrials.gov (NCT03829150) Dexlansoprazole MR-Based Concomitant Quadruple Therapy