Details of the Drug Combinations

General Information of This Drug (ID: DM2IXK8)

Drug Name

ADS-5102 DM2IXK8

Synonyms

Amantadine hydrochloride; 1-Adamantanamine hydrochloride; 665-66-7; 1-Aminoadamantane hydrochloride; Amantadine HCl; Mydantane; Midantan; Midantane; Amazolon; adamantan-1-amine hydrochloride; 1-Adamantylamine hydrochloride; Adamantanamine hydrochloride; Virofral; Influenol; Trivaline; Viregyt; Virasol; Amantan; Virosol; Adamantylamine hydrochloride; Aminoadamantane hydrochloride; Adamantine hydrochloride; 1-Adamantanamine, hydrochloride; NSC 83653; EXP 105-1; Tricyclodecane; Mantadix; Exp-105-1; Amantadine (hydrochloride); UN

Indication

Disease Entry	ICD 11	Status	REF
Dyskinesia	MB47.4	Phase 3	[1]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
ADS-5102 + Idarubicin	DC6OH3X	Idarubicin	Glioblastoma? (Cell Line: T98G)	[2]
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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.