Details of the Drug Combinations

General Information of This Drug (ID: DM4OS15)

Drug Name

UNBS-5162 DM4OS15

Synonyms

UNBS-5162; 956590-23-1; UNBS5162; UNII-JY9JF7D78N; UNBS 5162; JY9JF7D78N; 1-(2-(2-(dimethylamino)ethyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-5-yl)urea; WCKZRLOUKYFJDY-UHFFFAOYSA-N; SCHEMBL4188839; SCHEMBL4188846; UNBS 5162; AOB6480; EX-A460; BCP23948; ZINC34894706; UNBS 5162;UNBS-5162; AKOS026750504; CS-3379; Urea, N-(2-(2-(dimethylamino)ethyl)-2,3-dihydro-1,3-dioxo-1H-benz(de)isoquinolin-5-yl)-; HY-16509; DA-40120; QC-11792; KB-81386; BC600673; FT-0700422; Z-3223; J-690410

Indication

Disease Entry	ICD 11	Status	REF
Lymphoma	2A80-2A86	Phase 1	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
UNBS-5162 + Panobinostat	DCNUCUE	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[2]
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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027062)
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.