General Information of This Drug (ID: DM59UDI)

Drug Name
AZ-23   DM59UDI
Synonyms AZ-64; Trk inhibitors (cancer); Trk inhibitors (cancer), AstraZeneca
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
AZ-23 + Panobinostat DCDWCZ5 Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
------------------------------------------------------------------------------------

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.