Details of the Drug Combinations

General Information of This Drug (ID: DM6JN19)

Drug Name

ME-344 DM6JN19

Synonyms

NV-128; NV-344; MTOR inhibitor (cancer), Novogen; MTOR inhibitors (cancer), Marshall Edwards

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Phase 1/2	[1]
Solid tumour/cancer	2A00-2F9Z	Preclinical	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
ME-344 + Topotecan	DCZGTSY	Topotecan	Solid Tumors	[3]
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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7961).
3	ClinicalTrials.gov (NCT02100007) ME-344 Given in Combination With Hycamtin in Patients With Solid Tumors