Details of the Drug Combinations

General Information of This Drug (ID: DM9GRTK)

Drug Name

ACYLINE DM9GRTK

Synonyms

Acyline; UNII-S3439D3B35; CHEMBL262747; S3439D3B35; BDBM50102456; DB11906; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-(acetylamino)-L-phenylalanyl-4-(acetylamino)-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-; Z-3146; Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Aph(Ac)]-Leu-ILys-Pro-DAla-NH2

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 2	[1]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Testosterone + ACYLINE	DCDG6R9	Testosterone	Contraception	[2]
Testosterone + ACYLINE	DCFNP3R	Testosterone	Insulin Resistance	[3]
Testosterone + ACYLINE	DC4LSZU	Testosterone	Gonadotropin Deficiency	[1]
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References

1	ClinicalTrials.gov (NCT02147964) ITT-5 Mechanisms of Spermatogenesis. U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT00663793) ORAL T-6: Oral Androgens in Man-6
3	ClinicalTrials.gov (NCT01686828) T-IR- Study to Understand the Effects of Testosterone and Estrogen on the Body's Response to the Hormone Insulin