Details of the Drug Combinations

General Information of This Drug (ID: DMAPVRR)

Drug Name

Gentian violet DMAPVRR

Synonyms

Crystal violet; gentian violet; 548-62-9; Basic violet 3; Aniline Violet; Hexamethylpararosaniline chloride; Methylrosaniline chloride; Hexamethyl Violet; Gentiaverm; Pyoktanin; Vianin; Atmonil; Viocid; Avermin; Adergon; Axuris; Badil; Bismuth Violet; Methyl Violet 10B; Basic Violet BN; methylrosanilinium chloride; Gentioletten; Gentersal; Oxycolor; Genticid; Vermicid; Oxiuran; Oxyozyl; Calcozine Violet C; Meroxyl-Wander; Meroxylan-Wander; Brilliant Violet 5B; Hecto Violet R; Calcozine Violet 6BN; Violet CP; Crystal Violet O; Paper Blue R

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

10 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Gentian violet + Atovaquone	DCIOQ2H	Atovaquone	DD2 (Cell Line: DD2)	[2]
Gentian violet + Clindamycin	DCM38C4	Clindamycin	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Proguanil	DCIU2DZ	Proguanil	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Midostaurin	DCNQOVD	Midostaurin	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + GSK2126458	DCLUPPZ	GSK2126458	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Chloroquine	DC70XIL	Chloroquine	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Quinine	DC8P21H	Quinine	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Piperaquine	DCMQB7E	Piperaquine	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Atovaquone	DC2LOD8	Atovaquone	Hepatoblastoma (Cell Line: HB3)	[3]
Proguanil + Gentian violet	DCEWLQ2	Proguanil	DD2 (Cell Line: DD2)	[2]
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⏷ Show the Full List of 10 DrugCom(s)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3	Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.