Details of the Drug Combinations

General Information of This Drug (ID: DMAYD7O)

Drug Name
IT-141   DMAYD7O
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]

List of Combinatorial Drugs (CBD) Containing This Drug

175 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + IT-141 DCKJSSQ 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + IT-141 DCXKRU0 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Albendazole + IT-141 DCTEVXV Albendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Allopurinol + IT-141 DCZTSOB Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Amantadine + IT-141 DCAC5OH Amantadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + IT-141 DCVGT4Y Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + IT-141 DCSORQM Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Armodafinil + IT-141 DCRDWZK Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + IT-141 DCJATG9 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + IT-141 DCXMF84 Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Azatadine + IT-141 DCO3WK5 Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Baclofen + IT-141 DCT83O8 Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + IT-141 DCVR60C BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + IT-141 DC13ZO3 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bosentan + IT-141 DCV09QX Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Buspirone + IT-141 DCD8DV8 Buspirone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Busulfan + IT-141 DC2LZFT Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + IT-141 DCCOYXH Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilastatin + IT-141 DCJT254 Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + IT-141 DC2KT1P Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Citalopram + IT-141 DCNFCY5 Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Crotamiton + IT-141 DCDEGYC Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + IT-141 DC8EFY8 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Daidzin + IT-141 DCC2GJ2 Daidzin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + IT-141 DCL6NYB Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + IT-141 DCD158X Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dexmedetomidine + IT-141 DC4R6TN Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dextromethorphan + IT-141 DCH7RUJ Dextromethorphan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diazoxide + IT-141 DC9MRI6 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diethylcarbamazine + IT-141 DCP05OA Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dihydroergotamine + IT-141 DCL7BK1 Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + IT-141 DCQGG7F Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dopamine + IT-141 DCAOKRL Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Efavirenz + IT-141 DCS2U8V Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Eflornithine + IT-141 DCZYNSR Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + IT-141 DCLEU11 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Eptifibatide + IT-141 DCXWG7V Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Estramustine + IT-141 DC0LPMP Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ethinyl estradiol + IT-141 DCTG8V3 Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + IT-141 DC3FAQO ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Etomidate + IT-141 DCZTBPS Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Etonogestrel + IT-141 DCBWDQ3 Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fibrates + IT-141 DCI1O6Y Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Flavonoid derivative 1 + IT-141 DCXVXJ1 Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
FORMESTANE + IT-141 DCFSLY4 FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fosfomycin + IT-141 DCS6SZL Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GS4071 + IT-141 DCQ0DEO GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydralazine + IT-141 DCN4QV7 Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Isoproterenol + IT-141 DCCJLEU Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Ribavirin-TP DC7TQTH Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Lefaxin DCSUZLV Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Pentostatin DC4KC6W Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Primidone DCLOAIE Primidone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Gefitinib DCGO0O9 Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Paromomycin DCDCGA4 Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Aliskiren DCFHJH1 Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Diethylcarbamazine DC3EEIP Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Lumefantrine DCE542S Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Triamterene DC2YCF6 Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Imipramine DCII0IJ Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Terazosin DCGRNA8 Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Epinephrine DCF2SLS Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Furazolidone DC3R52Q Furazolidone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + GYKI-52466 DCJW6KW GYKI-52466 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Tacrine DC82WT6 Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Repaglinide DCQ2992 Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Mephenytoin DCSK32R Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Everolimus DCCBFA3 Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Everolimus DCG5UV8 Everolimus Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
IT-141 + Tranexamic acid DCBNDI6 Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + 10-hydroxycamptothecin DC3ST7W 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Pamidronate DCMP0PS Pamidronate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Methylergonovine DCBF3NN Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Isosorbide dinitrate DCMLK16 Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Guanfacine DCIOOJF Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Carglumic acid DC2RZJV Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + K-134 DCVNPC9 K-134 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Phenprocoumon DCWVSJO Phenprocoumon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + LY03004 DCR1VHE LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Methoxsalen DCAHQK4 Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Galantamine DCNNN5K Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Pazopanib DCCMQY6 Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Ginsenoside Rb1 DCGGT92 Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Fluspirilene DCNNWBA Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Armodafinil DCCJE9A Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Mecamylamine DCMTKK8 Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Dichlorphenamide DCT8XVK Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Naringenin DC89PS8 Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Diphenidol DCZX86Q Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Pentamidine DCJPUKN Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Procarbazine DCTTTIO Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Triflupromazine DCDTG7C Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Oseltamivir DCX0GUO Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Benserazide DCTNC5X Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Pargyline DCVK014 Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Idarubicin DCIQZP1 Idarubicin Glioblastoma? (Cell Line: T98G) [2]
IT-141 + BRL-15572 DCNXR0T BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + LEE011 DCVH9AU LEE011 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
IT-141 + Darunavir DCJ8NZ4 Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Atenolol DCSXKMA Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Pramipexole DCBP123 Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Ethinyl estradiol DC31Q7L Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Mesalazine DCB1WFQ Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Olanzapine DC3XT0A Olanzapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + BMS-754807 DCIYWBI BMS-754807 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
IT-141 + Teriflunomide DCK9OXA Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Ethambutol DCN1ZNK Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Novobiocin DCD8NCJ Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Chlorambucil DCD7169 Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Acarbose DC4G0X9 Acarbose Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Bumetanide DCXMW4F Bumetanide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Brincidofovir DCPVIVH Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Sorafenib DCN2W3T Sorafenib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Endoxifen DCHXSAY Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Hydralazine DC6R5DG Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Cisatracurium DCBW3GP Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Iloprost DCF7JRG Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Zileuton DCC6FEH Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Silver sulfadiazine DCFCHM4 Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Testolactone DCOIBPS Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + PMID28870136-Compound-43 DC5PHXE PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Vorinostat DC72CUA Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Cevimeline DCKMEBG Cevimeline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Cerivastatin DCE0EWS Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Metaxalone DCZM44R Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Hydroxychloroquine DCFBY63 Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Atovaquone DCBOH6D Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Aciclovir DCZ5R5L Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + AS-1949490 DCJR4Y2 AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + GSK2194069 DC4VVK8 GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Tacrolimus DCN5THK Tacrolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + L-165041 DC96ME2 L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Ruxolitinib DCIUQ35 Ruxolitinib Hodgkin lymphoma (Cell Line: L-1236) [3]
Itraconazole + IT-141 DCP7TU3 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + IT-141 DCUJFHR Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Linagliptin + IT-141 DCIDZP9 Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lithium Citrate + IT-141 DCV80MT Lithium Citrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lubiprostone + IT-141 DCBWSKF Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + IT-141 DCC2DLJ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mebendazole + IT-141 DCB92ZK Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mebutamate + IT-141 DC6193T Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Memantine + IT-141 DCZBCVU Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Miglustat + IT-141 DCU0JZC Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mitapivat + IT-141 DCX1A9W Mitapivat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
ML323 + IT-141 DCCQL62 ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nabilone + IT-141 DCFZK0L Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Naltrexone + IT-141 DCCRIBI Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Niclosamide + IT-141 DCRIBPF Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nitisinone + IT-141 DCQ2JR9 Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Olmesartan medoxomil + IT-141 DCV9MZD Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + IT-141 DCZD6W7 Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentamidine + IT-141 DCT9Z9I Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Picoplatin + IT-141 DCGOHH1 Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pinacidil + IT-141 DCTY8LO Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + IT-141 DC2E8W9 Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Quinine + IT-141 DCWUATR Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Raltegravir + IT-141 DCG3RGD Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ramelteon + IT-141 DCR3LX9 Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Rifampin + IT-141 DC7MY2G Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
SCH 727965 + IT-141 DCZX4UN SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sulfapyridine + IT-141 DC2TJFX Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sumatriptan + IT-141 DCRRV7Z Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terameprocol + IT-141 DC15PEO Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone + IT-141 DCW8E7C Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone cypionate + IT-141 DCQDTME Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tolazoline + IT-141 DCDA5HL Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tolvaptan + IT-141 DCN9DON Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trifluoperazine + IT-141 DC9T13A Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triflupromazine + IT-141 DCETN8D Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trihexyphenidyl + IT-141 DCU7BFZ Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triiodothyronine + IT-141 DCCK1K4 Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + IT-141 DC95MK8 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trioxsalen + IT-141 DCIVRWB Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tropisetron + IT-141 DCOIMD7 Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
WAY-100635 + IT-141 DCKBZYY WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.