Details of the Drug Combinations

General Information of This Drug (ID: DMBLM5H)

Drug Name
BHV-0223   DMBLM5H
Indication
Disease Entry ICD 11 Status REF
Amyotrophic lateral sclerosis 8B60.0 Phase 1 [1]

List of Combinatorial Drugs (CBD) Containing This Drug

68 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + BHV-0223 DCDK0ZH Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohydroxamic Acid + BHV-0223 DCL2XUG Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Allopurinol + BHV-0223 DCGJVWB Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + BHV-0223 DCGB4W8 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Gefitinib DCRWL9K Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Paromomycin DC55TZU Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Epinephrine DC9O15D Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + PMID28460551-Compound-2 DCKNRM0 PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Sivelestat DCIL2ES Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Fomepizole DCW6M4I Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + IT-141 DCVR60C IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Testosterone cypionate DC6UY5S Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Terameprocol DC5Z9WU Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Emetine DCGI2CD Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Chlorzoxazone DC1XC3S Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Docetaxel DCJ4GHV Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + JZL195 DC6K6MV JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Ginsenoside Rb1 DCZZXJT Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Armodafinil DCM7F78 Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Zaleplon DC66AAO Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Naringenin DCBXAD3 Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Clopidogrel DCFEYM2 Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + BIO-300 DC5L0GF BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Diazoxide DCJNV3G Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Idarubicin DCVCPD6 Idarubicin Glioblastoma? (Cell Line: T98G) [2]
BHV-0223 + Probenecid DC5NQED Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Bortezomib DCJ45CG Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Methylene blue DC8WRQE Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Oxyphenbutazone DC6UPS0 Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Eptifibatide DCJREEI Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Brincidofovir DC7RANM Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Amantadine DCSZXIT Amantadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Hyodeoxycholic acid DC7DI0F Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Hydralazine DC1I72Y Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Pyronaridine DCTZF98 Pyronaridine DD2 (Cell Line: DD2) [2]
BHV-0223 + Cisatracurium DC4P7OP Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Lacosamide DCI5MN0 Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Doxorubicin DC6UIXQ Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Auranofin DC75DFZ Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Cerivastatin DC9P25C Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Enoxacin DCMUTEJ Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BHV-0223 + Lumefantrine DCK6LV6 Lumefantrine Hepatoblastoma (Cell Line: HB3) [3]
BHV-0223 + Mefloquine DCHMUYW Mefloquine Hepatoblastoma (Cell Line: HB3) [3]
Cerivastatin + BHV-0223 DCETT3E Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorambucil + BHV-0223 DCBD8CA Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chloroquine + BHV-0223 DC4HJER Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + BHV-0223 DC5OBGO Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Etonogestrel + BHV-0223 DCPK5EO Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Everolimus + BHV-0223 DCDOCX1 Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydralazine + BHV-0223 DCMQDGQ Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + BHV-0223 DCAP8SE L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + BHV-0223 DC0G0FF Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Loperamide + BHV-0223 DC8VCKT Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + BHV-0223 DC634JK Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maraviroc + BHV-0223 DC5JJSC Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metformin + BHV-0223 DCQQU9I Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methoxsalen + BHV-0223 DCNGDNI Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Olmesartan medoxomil + BHV-0223 DCME9AC Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pepstatin + BHV-0223 DCLXPI6 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PF-02545920 + BHV-0223 DC7M6QM PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PHA-739358 + BHV-0223 DCWO2J8 PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Quinine + BHV-0223 DCIHUHB Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
SCH 727965 + BHV-0223 DCLX0Z9 SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Theophylline + BHV-0223 DC9WL6Z Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Topotecan + BHV-0223 DCJ2L5I Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + BHV-0223 DCOTMHC Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + BHV-0223 DC9SYIS Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vinblastine + BHV-0223 DCLD6YY Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 68 DrugCom(s)

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.