Details of the Drug Combinations

General Information of This Drug (ID: DMEB837)

Drug Name

Cefotaxime DMEB837

Synonyms

Cefotaxima; Cefotaxima [INN-Spanish]; Cefotaxime [INN:BAN]; Cefotaxime acid; Cefotaximum; Cefotaximum [INN-Latin]; Cephotaxime; E-cefotaxime; Omnatax; RU 24662; RU 24756; cefotaxime; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, (6R,7R)-; 60846-21-1; 63527-52-6; C16H17N5O7S2; CHEBI:204928; EINECS 264-299-1; HR 756; N2GI8B1GK7; Taxim; UNII-N2GI8B1GK7

Indication

Disease Entry	ICD 11	Status	REF
Bacteremia	1A73	Approved	[1]
Bacterial arthritis	N.A.	Approved	[1]
Bacterial infection	1A00-1C4Z	Approved	[2]
Escherichia coli meningitis	N.A.	Approved	[1]
Meningococcal meningitis	N.A.	Approved	[1]
Neonatal sepsis	N.A.	Approved	[1]
Peritonitis	N.A.	Approved	[1]
Staphylococcal pneumonia	N.A.	Approved	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of Indication(s)

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Cefotaxime + Metronidazole	DCCXROK	Metronidazole	Appendicitis	[3]
Cefotaxime + Azithromycin	DCZ8GI2	Azithromycin	Cirrhosis	[4]
------------------------------------------------------------------------------------

References

1	Cefotaxime FDA Label
2	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 064200.
3	ClinicalTrials.gov (NCT02404064) Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?
4	ClinicalTrials.gov (NCT01820026) Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis