Details of the Drug Combinations

General Information of This Drug (ID: DMFK9HG)

• Drug Name: Escitalopram (DMFK9HG)
• Synonyms: Esertia; Escitalopram [INN]; Cipralex (TN); Escitalopram (INN); Esertia (TN); Lexapro (TN); S(+)-Citalopram; (+)-(S)-1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile; (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile; (S)-Citalopram

Indication

Major depressive disorder; ICD 11: 6A70.3; Status: Approved [1]

• Therapeutic Class: Antidepressants
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

17 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Aripiprazole + Escitalopram	DCB2N18	Aripiprazole	Major Depressive Disorder (MDD)	[2]
Bupropion + Escitalopram	DCQVJ7Z	Bupropion	Depression	[3]
Escitalopram + Mirtazapine	DC05J0L	Mirtazapine	Major Depressive Disorder	[4]
Escitalopram + Gaboxadol	DC0ZUQX	Gaboxadol	Major Depressive Disorder	[5]
Escitalopram + Desipramine	DC1L9I6	Desipramine	Depression	[6]
Escitalopram + Saredutant	DC8Z2DS	Saredutant	Major Depressive Disorder	[7]
Escitalopram + Pramipexole	DCH0Z2Z	Pramipexole	Major Depression	[8]
Escitalopram + Acamprosate	DCI7K4U	Acamprosate	Major Depressive Disorder	[9]
Escitalopram + Clomipramine	DCMIO39	Clomipramine	Obsessive Compulsive Disorder	[10]
Escitalopram + Vildagliptin	DCPLTNE	Vildagliptin	Major Depressive Disorder	[11]
Eszopiclone + Escitalopram	DC6ZDAA	Eszopiclone	Insomnia	[12]
Ethosuximide + Escitalopram	DCQUOKR	Ethosuximide	Depressive Disorder, Treatment-Resistant	[13]
Ramelteon + Escitalopram	DCJYIJZ	Ramelteon	Major Depressive Disorder	[14]
Memantine + Escitalopram	DC7E1VA	Memantine	Mild Cognitive Impairment	[15]
Pregabalin + Escitalopram	DC3T2WJ	Pregabalin	Burning Mouth Syndrome	[16]
Duloxetine + Escitalopram	DCNHSBC	Duloxetine	Post Traumatic Stress Disorder	[17]
Escitalopram + OPC-34712	DCMB850	OPC-34712	Major Depressive Disorder	[18]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] ClinicalTrials.gov (NCT01123707) To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)
• [3] ClinicalTrials.gov (NCT00917059) Personalized Indicators for Predicting Response to SSRI Treatment in Major Depression (The PRISE-MD Study)
• [4] ClinicalTrials.gov (NCT01764867) Algorithm Guided Treatment Strategies for Major Depressive Disorder
• [5] ClinicalTrials.gov (NCT00807248) Short-term Study of Combination Treatment of Escitalopram and Gaboxadol in Major Depressive Disorder
• [6] ClinicalTrials.gov (NCT00456014) Pre-Treatment Positron Emission Topography Scanning for Increasing Success in Antidepressant Treatment
• [7] ClinicalTrials.gov (NCT00531622) An Eight-week Study of Saredutant and Escitalopram as Combination Treatment for Major Depressive Disorder
• [8] ClinicalTrials.gov (NCT00086307) Lexapro and Pramipexole and to Treat Major Depression
• [9] ClinicalTrials.gov (NCT00452543) Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism
• [10] ClinicalTrials.gov (NCT01404871) Predicting Medication Response in Obsessive Compulsive Disorder
• [11] ClinicalTrials.gov (NCT04410341) The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients
• [12] ClinicalTrials.gov (NCT00813735) Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder
• [13] ClinicalTrials.gov (NCT03887624) Investigate the Clinical Responses of Ethosuximide in Patients With Treatment-Resistant Depression.
• [14] ClinicalTrials.gov (NCT00642694) Time to Remission of Depressive Symptoms With Combined SSRI and Ramelteon
• [15] ClinicalTrials.gov (NCT01876823) Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment
• [16] ClinicalTrials.gov (NCT06025474) Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome
• [17] ClinicalTrials.gov (NCT04697693) Antidepressant Response in Older Adults With Comorbid PTSD and MDD
• [18] ClinicalTrials.gov (NCT05017311) Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)