Details of the Drug Combinations

General Information of This Drug (ID: DMFT5D6)

Drug Name

Telcagepant DMFT5D6

Synonyms

MK 0974; MK0974; N7R; MK-0974; Telcagepant (USAN); N-(6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl)-4-(2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridin-1-yl)piperidine-1-carboxamide

Indication

Disease Entry	ICD 11	Status	REF
Cluster headache	8A81.0	Phase 2	[1]
Migraine	8A80	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Ibuprofen + Telcagepant	DCOMG2L	Ibuprofen	Migraine	[2]
Telcagepant + Acetaminophen	DCI98I8	Acetaminophen	Migraine	[2]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 703).
2	ClinicalTrials.gov (NCT00758836) A Study to Test the Safety and Effectiveness of MK-0974 (Telcagepant) Co-administered With Ibuprofen or Acetaminophen in Patients With Migraines With or Without Aura (MK-0974-046)