Details of the Drug Combinations

General Information of This Drug (ID: DMFZBMQ)

Drug Name

CHLOROXINE DMFZBMQ

Synonyms

chloroxine; 5,7-Dichloroquinolin-8-ol; 773-76-2; 5,7-Dichloro-8-hydroxyquinoline; Chlorquinol; Quixalin; Capitrol; Dichloroxin; Chloroxyquinoline; Dichloroquinolinol; Dikhloroskin; 5,7-Dichloro-8-quinolinol; Endiaron; Clofuzid; Quinolor; Dichlorohydroxyquinoline; Chlofucid; Quesyl; 5,7-Dichloroxine; 5,7-Dichlorooxine; Chlorohydroxyquinoline; 8-QUINOLINOL, 5,7-DICHLORO-; 5,7-Dichloro-8-oxyquinoline; Chloroxine [USAN]; 5,7-Dichlor-8-hydroxychinolin; C9H5Cl2NO; NSC 3904; UNII-2I8BD50I8B; CCRIS 5751; CHQ; Capitrol Cream Shampoo; EINECS 212-2

Indication

Disease Entry	ICD 11	Status	REF
Erythema	ME64.0	Approved	[1]
Pityriasis simplex	N.A.	Approved	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

11 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Chloroquine + Chloroxine	DCAWF06	Chloroquine	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
Chloroquine + Chloroxine	DC8WGZF	Chloroquine	Primitive neuroectodermal tumor (Cell Line: TC-32)	[3]
Chloroxine + Cantharidin	DC92I69	Cantharidin	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
Chloroxine + Idarubicin	DCANSBZ	Idarubicin	Glioblastoma? (Cell Line: T98G)	[3]
Chloroxine + Mefloquine	DCYMBL4	Mefloquine	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
Chloroxine + Mefloquine	DCRFFQL	Mefloquine	Primitive neuroectodermal tumor (Cell Line: TC-32)	[3]
Chloroxine + Vinpocetine	DCR7YFJ	Vinpocetine	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
RAF265 + Chloroxine	DCCCLQG	RAF265	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
SNDX-275 + Chloroxine	DCJ77B6	SNDX-275	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
THAPSIGARGIN + Chloroxine	DCBSMVM	THAPSIGARGIN	Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII)	[3]
THAPSIGARGIN + Chloroxine	DCET5EB	THAPSIGARGIN	Primitive neuroectodermal tumor (Cell Line: TC-32)	[3]
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⏷ Show the Full List of 11 DrugCom(s)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Chloroxine FDA Label
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.