Details of the Drug Combinations

General Information of This Drug (ID: DMGQFYB)

Drug Name
Mecamylamine   DMGQFYB
Synonyms
Mecamilamina; Mecamine; Mecamylaminum; Mekamine; Mevasine; Revertina; Versamine; Inversine hydrochloride; Mecamilamina [DCIT]; Mecamilamina [Italian]; Mevasin hydrochloride; Inversine (TN); Mecamylamine [INN:BAN]; Mecamylaminum [INN-Latin]; N-Methyl-2-isocamphanamine; N,2,3,3-Tetramethyl-2-norbornamine; N,2,3,3-Tetramethyl-2-norcamphanamine; N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine; 2-Methylamino-2,3,3-trimethylnorbornane; 2-Methylaminoisocamphane; 3-Methylaminoisocamphane; 3-Methylaminoisokamfan; 3-Methylaminoisokamfan [Czech]; 3-beta-Methylamino-2,2,3-trimethylbicyclo(2.2.1)heptane
Indication
Disease Entry ICD 11 Status REF
Essential hypertension BA00 Approved [1]
Therapeutic Class
Antihypertensive Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

50 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Mecamylamine DCF950E Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aciclovir + Mecamylamine DC0GDMJ Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + Mecamylamine DCD8PD8 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Atenolol + Mecamylamine DCGTQD1 Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Mecamylamine DCJW6EN BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Mecamylamine DCCFPVO Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Mecamylamine DCQP4V3 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Busulfan + Mecamylamine DC372FA Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Mecamylamine DC4KZLO Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fomepizole + Mecamylamine DCNTFQX Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Mecamylamine DCMTKK8 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Mecamylamine DCRUMY4 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
LY03004 + Mecamylamine DCBEZ5G LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Mebutamate DCXXN9A Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Bepridil DCZRL8T Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Gefitinib DCX8TNN Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Paromomycin DCOV45X Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Acitretin DCL38XO Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Everolimus DCPPMDU Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Dexmedetomidine DCY9BK0 Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Palonosetron DCL9CVR Palonosetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Metyrosine DCRDKZW Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Efavirenz DCOKFB5 Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Terameprocol DCZYI6T Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + SCH 727965 DCRZNEZ SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + JZL195 DCD6W7M JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + PF-02545920 DCQCGG7 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Tiagabine DC01M1S Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Diazoxide DCS2QAB Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Idarubicin DCQW3SP Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Imatinib DCBSR9C Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Methylene blue DC2U3FN Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Clascoterone DCAV71X Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Trimethobenzamide DCUFDEE Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Maprotiline DC1LB8Q Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Leflunomide DC413CL Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Chlorambucil DCKHSLF Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Brincidofovir DC7Y7LV Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Hyodeoxycholic acid DC3X7HN Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Mefloquine DC0C4ZD Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Cevimeline DC4AWGL Cevimeline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Cerivastatin DCWAW7J Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Metaxalone DC2FQJV Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methotrexate + Mecamylamine DCJLEOI Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Rufinamide + Mecamylamine DC9PY2N Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sumatriptan + Mecamylamine DCLTIXP Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tolvaptan + Mecamylamine DCI7TSA Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Topotecan + Mecamylamine DC5YI7S Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + Mecamylamine DCA3H0X Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Mecamylamine DC0N726 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 50 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.