Details of the Drug Combinations

General Information of This Drug (ID: DMHG57U)

Drug Name

OPC-34712 DMHG57U

Synonyms

Brexpiprazole

Indication

Disease Entry	ICD 11	Status	REF
Major depressive disorder	6A70.3	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Sertraline + OPC-34712	DCMTBU3	Sertraline	Post Traumatic Stress Disorder	[2]
Escitalopram + OPC-34712	DCMB850	Escitalopram	Major Depressive Disorder	[3]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7672).
2	ClinicalTrials.gov (NCT04124614) Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD
3	ClinicalTrials.gov (NCT05017311) Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)