Details of the Drug Combinations

General Information of This Drug (ID: DMHPWOM)

Drug Name
Diphenidol   DMHPWOM
Synonyms
Avomol; Defenidol; Difenidol; Difenidolo; Difenidolum; Nometic; Vontrol; Difenidol HCl; Difenidolo [DCIT]; SKF 478; Difenidolum [INN-Latin]; Diphenidol [USAN:BAN]; SK-478; Diphenidol (USAN/INN); SK&F-478; Alpha,alpha-Diphenyl-1-piperidinebutanol; Diphenyl(3-(1-piperidyl)propyl)carbinol; 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol; 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol hydrochloride
Indication
Disease Entry ICD 11 Status REF
Nausea MD90 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

100 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Diphenidol DCT5XNO Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acitretin + Diphenidol DCD95ZT Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Albendazole + Diphenidol DCUYATA Albendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Allopurinol + Diphenidol DCGJ27T Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + Diphenidol DCAJZEO Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + Diphenidol DCDH9WB Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Diphenidol DCL9AEF BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Diphenidol DCB16AX Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BRL-15572 + Diphenidol DCE1DTE BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + Diphenidol DCH600S Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cycloguanil + Diphenidol DCQ9F5V Cycloguanil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Diphenidol DCIVM6I Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Daidzin + Diphenidol DCLC96E Daidzin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Lefaxin DCUMZI7 Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Gefitinib DCUARDO Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Acetazolamide DC4IA5I Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Paromomycin DCMEWXI Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Diethylcarbamazine DCB0ZC2 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Kanamycin DCOEKTK Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Citalopram DCSWONQ Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Epinephrine DCYCPLU Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + PMID28460551-Compound-2 DCXXNHE PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Trioxsalen DCAXOSW Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Methotrexate DCV0TI8 Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Miglustat DCTCTU9 Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Pazopanib HCl DCT6ETP Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Testosterone DCTVUUD Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Triapine DC8DTWI Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + IT-141 DCQGG7F IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Metyrosine DCA1SVZ Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Terameprocol DCZIKEX Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Guanfacine DCOKE53 Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Itraconazole DCEXZZE Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Chlorzoxazone DC3LQHV Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Docetaxel DCUASAK Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Aminosalicylic acid DC6ABD2 Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + JZL195 DCV4SRO JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Sulfinpyrazone DCLUK46 Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Ginsenoside Rb1 DCW0ZY0 Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Clopidogrel DCBB8AB Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Triflupromazine DC6QWGU Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + PF-02545920 DCMK55P PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Isoproterenol DCLO9B5 Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Oseltamivir DCTJXJO Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Ibutilide DC3ZA5T Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + GINKGOLIDE A DCO8AM8 GINKGOLIDE A Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Diazoxide DCHAFQL Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Fenoprofen DCYGELA Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Pargyline DC2UR6F Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Methocarbamol DCR1L5Y Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Imatinib DCWBY8B Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Bortezomib DCZ2G8V Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Methylene blue DCRGEGV Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Tropisetron DCN388U Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Acamprosate DCDGQN0 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Trimethobenzamide DC9S2B9 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Maprotiline DCUJGQ2 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Oxyphenbutazone DCFAN3F Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Leflunomide DCGXXXB Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Novobiocin DCDETCS Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Chlorambucil DCR57TZ Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Chloroquine DCOB1CD Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Pomalidomide DCQOAH0 Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Endoxifen DCL4DAL Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Mycophenolic acid DCGRFPM Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Cisatracurium DC3SOD0 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Doxorubicin DCDV7XS Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Zileuton DCWXESK Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Nabilone DCA0NW0 Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Testolactone DCUUTPB Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Vorinostat DC3IOSM Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Cerivastatin DCOJKTS Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Aciclovir DCOSKLK Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Albendazole DCJYKGC Albendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Diphenidol DCKKNY3 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Diphenidol DCPJA03 Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
FORMESTANE + Diphenidol DCF1339 FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ginsenoside Rb1 + Diphenidol DCHGOCA Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hyodeoxycholic acid + Diphenidol DCV7GU3 Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Idarubicin + Diphenidol DC4E225 Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Diphenidol DCKVL9R Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
IT-141 + Diphenidol DCZX86Q IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Kanamycin + Diphenidol DCM90UP Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lacosamide + Diphenidol DCX2HQ9 Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Leflunomide + Diphenidol DCPU0SF Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Diphenidol DCX7EW3 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Diphenidol DC6Z4KN Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mebutamate + Diphenidol DCTSTV6 Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib + Diphenidol DCYALCC Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pizotyline + Diphenidol DCY8FHG Pizotyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PMID28460551-Compound-2 + Diphenidol DC8VXAD PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Probenecid + Diphenidol DCU5YYQ Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + Diphenidol DCS3WGY Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sulfapyridine + Diphenidol DCUQPEW Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Topotecan + Diphenidol DC4JXH6 Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + Diphenidol DC9ZEI2 Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trioxsalen + Diphenidol DCXNWCR Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Diphenidol DCGYUHX Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
VR-776 + Diphenidol DCL0QF4 VR-776 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Zaleplon + Diphenidol DCUL82E Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7163).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.