General Information of This Drug (ID: DMHQEA0)

Drug Name
Oltipraz   DMHQEA0
Synonyms
CB-1400; Oltipraz (mucositis/radiation sickness/cancer); Oltipraz (mucositis/radiation sickness/cancer), Canopus Biopharma; Syntheticdithiolethione (oral, acute radiation syndrome/mucositis/cancer), Canopus
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Oltipraz + Marizomib DCIKUAD Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
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References

1 ClinicalTrials.gov (NCT02068339) Efficacy and Safety of Oltipraz for Liver Fat Reduction in Patients With Non-Alcoholic Fatty Liver Disease Except for Liver Cirrhosis. U.S. National Institutes of Health.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.