Details of the Drug Combinations

General Information of This Drug (ID: DMIEU69)

Drug Name
Salmeterol   DMIEU69
Synonyms
Aeromax; Astmerole; SALMATEROL; Salmeterolum; Serevent; Glaxo Wellcome brand of salmeterol xinafoate; Salmeterolum [Latin]; GR 33343X; S 2692; GR-33343X; Serevent (TN); Salmeterol (USAN/INN); Salmeterol [USAN:BAN:INN]; (+-)-4-Hydroxy-alpha'-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-m-xylene-alpha,alpha'-diol; (+-)-4-Hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedimethanol; (inverted question mark) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol; 2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol; 2-(hydroxymethyl)-4-[1-hydroxy-2-({6-[(4-phenylbutyl)oxy]hexyl}amino)ethyl]phenol; 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol
Indication
Disease Entry ICD 11 Status REF
Allergic asthma CA23.0 Approved [1]
Chronic obstructive pulmonary disease CA22 Approved [2]
Intrinsic asthma N.A. Approved [1]
Pulmonary emphysema CA21.Z Approved [1]
Therapeutic Class
Bronchodilator Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

5 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Fluticasone + Salmeterol DCVFYDT Fluticasone COPD [3]
Salmeterol + Formoterol DC5LFA0 Formoterol Asthma [4]
Salmeterol + Fluticasone propionate DCYZFC5 Fluticasone propionate Allergic Asthma [5]
Fluticasone + Salmeterol DCVVFQ2 Fluticasone Chronic Obstructive Pulmonary Disease [6]
Fluticasone + Salmeterol DC4MBMX Fluticasone Chronic Obstructive Pulmonary Disease [6]
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1 Approved Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Salmeterol + Fluticasone propionate DCU6QC9 Fluticasone propionate Asthma [7]
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References

1 Salmeterol FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 559).
3 ClinicalTrials.gov (NCT00568347) Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
4 ClinicalTrials.gov (NCT01290874) Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)
5 ClinicalTrials.gov (NCT00214019) The Effect of Salmeterol on Eosinophil (EOS) Function
6 ClinicalTrials.gov (NCT02055352) Study to Evaluate Efficacy/Safety of Combination Budesonide/Indacaterol vs Fluticasone/Salmeterol in Patients With COPD
7 UniProt: the universal protein knowledgebase. Nucleic Acids Res. 2017 Jan 4;45(D1):D158-D169. (ID: O95477)