Details of the Drug Combinations

General Information of This Drug (ID: DMIY6DB)

Drug Name
Verteporfin   DMIY6DB
Synonyms Visudyne (TN)
Indication
Disease Entry ICD 11 Status REF
Choroidal neovascularization 9B76 Approved [1]
Exudative age-related macular degeneration 9B78.3Z Approved [1]
Psoriasis vulgaris EA90 Approved [2]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

18 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
ABT-263 + Verteporfin DCLT2QL ABT-263 Ewing sarcoma (Cell Line: TC-71) [3]
Nintedanib + Verteporfin DC00JP2 Nintedanib Ewing sarcoma (Cell Line: TC-71) [4]
OSI-027 + Verteporfin DCH4415 OSI-027 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + OZ277 DC0VO2B OZ277 DD2 (Cell Line: DD2) [4]
Verteporfin + MK-1775 DCLS3C5 MK-1775 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + Artemether DCDNUTT Artemether Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + AZD8055 DCXFRLV AZD8055 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + Everolimus DCGRUUR Everolimus Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + SCH 727965 DCBTXWV SCH 727965 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + Docetaxel DCRNHBC Docetaxel Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + THAPSIGARGIN DCM7OGP THAPSIGARGIN Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + Cycloheximide DCB5UN4 Cycloheximide Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + OSI-906 DC4MXRC OSI-906 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + Tivantinib DCQL6GE Tivantinib Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + TG100801 DCK70EY TG100801 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + AXL-1717 DCCOUD0 AXL-1717 Ewing sarcoma (Cell Line: TC-71) [4]
Verteporfin + Trametinib DCLNU90 Trametinib Embryonal rhabdomyosarcoma (Cell Line: CTR) [3]
Verteporfin + Trametinib DCMHQGZ Trametinib Embryonal rhabdomyosarcoma (Cell Line: RD) [3]
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⏷ Show the Full List of 18 DrugCom(s)
1 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Verteporfin + Aflibercept DCREGW2 Aflibercept Macular Degeneration [5]
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References

1 Verteporfin FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
4 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
5 ClinicalTrials.gov (NCT01746875) A Study Testing if Medicine Can Make Pigment Epithelium Detachments Regress and Stabilize the Vision in Eyes