Details of the Drug Combinations

General Information of This Drug (ID: DMJ7IKW)

Drug Name

PF-4494700 DMJ7IKW

Synonyms

PF-04494700; TTP-488; TTP-488); Alzheimers therapy, TransTech/Pfizer; Diabetic nephropathy therapy, Transtech/Pfizer; Alzheimer'streatment, TransTech/Pfizer; Alzheimer's therapy (RAGE), Transtech/Pfizer

Indication

Disease Entry	ICD 11	Status	REF
Alzheimer disease	8A20	Phase 3	[1]
Dementia	6D80-6D86	Phase 3	[2]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Dexamethasone + PF-4494700	DCXVAYA	Dexamethasone	Cancer	[3]
PF-4494700 + PF-4494700	DCR127T	PF-4494700	Glioblastoma	[4]
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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8317).
3	ClinicalTrials.gov (NCT05789589) Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases
4	ClinicalTrials.gov (NCT05635734) Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma