Details of the Drug Combinations

General Information of This Drug (ID: DMLU8NX)

Drug Name
Benserazide   DMLU8NX
Synonyms
benserazide; Serazide; 322-35-0; Benseraszide; Benserazida; Benserazidum; Ro 4-4602; Ro 44602; DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide; Benserazidum [INN-Latin]; Benserazida [INN-Spanish]; Benserazide [USAN:INN:BAN]; DL-Seryltrihydroxybenzylhydrazine; C10H15N3O5; BRN 3984490; DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; CHEBI:64187; DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-; DL-serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

52 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Benserazide + Aprepitant DC14UFI Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Lefaxin DCLRXEM Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Gefitinib DCX9Q9N Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Diethylcarbamazine DCY2K2D Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Epinephrine DC3CB8H Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Everolimus DCGYKHP Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Metyrosine DCG3LBE Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Sitagliptin DCZVGWU Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + PF-02545920 DCSFBCM PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Fenoprofen DC5RFZF Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Entacapone DCE3BPZ Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Probenecid DCJMSZ5 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Pramipexole DC8BGNF Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Bortezomib DCFTES2 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Methylene blue DC89OWB Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Brincidofovir DCTQ9F9 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Auranofin DCOZY58 Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Cerivastatin DCP66QN Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Albendazole DCL06RP Albendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Benserazide + Cytarabine DC0HO70 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
BIO-300 + Benserazide DCO4M7Q BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Brincidofovir + Benserazide DCNBLWB Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Chlorzoxazone + Benserazide DCMOYAS Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Cinacalcet + Benserazide DC1HJ9Z Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Cisatracurium + Benserazide DCSNAI8 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Clindamycin + Benserazide DCTVE27 Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Dantrolene + Benserazide DCK0MD7 Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Diazoxide + Benserazide DCULFA7 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Docetaxel + Benserazide DC4V7RR Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Doxorubicin + Benserazide DCTPXL9 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Endoxifen + Benserazide DCN3CSJ Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Eptifibatide + Benserazide DCG6SYW Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Ezetimibe + Benserazide DCZ2NVP Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Fomepizole + Benserazide DCHYXQ4 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Imatinib + Benserazide DCN1B66 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
IT-141 + Benserazide DCTNC5X IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Leflunomide + Benserazide DCUZRGQ Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Loperamide + Benserazide DC8CC5I Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Maprotiline + Benserazide DC5XNC2 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Methoxsalen + Benserazide DCRVEO9 Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Mycophenolic acid + Benserazide DCQCHC2 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Pepstatin + Benserazide DC3R47O Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
PHA-739358 + Benserazide DCAR5JF PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Pyrazinamide + Benserazide DCPGG84 Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Ramelteon + Benserazide DCAFAV7 Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Sumatriptan + Benserazide DCK8TRH Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Tetracycline + Benserazide DCV75R9 Tetracycline Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Topotecan + Benserazide DCSI8BZ Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + Benserazide DCP04L2 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triflupromazine + Benserazide DCH43GC Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Trimethobenzamide + Benserazide DCKALCI Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
Vorinostat + Benserazide DCAYKUM Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [1]
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⏷ Show the Full List of 52 DrugCom(s)

References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
2 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.