Details of the Drug Combinations

General Information of This Drug (ID: DMN8E5D)

Drug Name
Sunitinib malate   DMN8E5D
Synonyms
(Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (S)-2-hydroxysuccinate; LVX8N1UT73; MFCD08282795; N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-hydroxybutanedioate; PHA-290940AD; SU 011248; SU010398; SU011248; SU011248 L-malate salt; SUNITINIB MALEATE; Sunitinib malate; Sunitinib malate [USAN]; UNII-LVX8N1UT73
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

10 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Colchicine + Sunitinib malate DC66TWZ Colchicine Lymphoid neoplasm (Cell Line: Mak) [1]
Mizoribine + Sunitinib malate DCZUKWW Mizoribine Lymphoid neoplasm (Cell Line: Mak) [1]
Omacetaxine mepesuccinate + Sunitinib malate DCC3LG6 Omacetaxine mepesuccinate Hepatocellular carcinoma (Cell Line: Huh-7) [1]
Omacetaxine mepesuccinate + Sunitinib malate DC5CX3C Omacetaxine mepesuccinate Lymphoid neoplasm (Cell Line: Mak) [1]
Ospemifene + Sunitinib malate DCH4M83 Ospemifene Lymphoid neoplasm (Cell Line: Mak) [1]
Sunitinib malate + DZNep DCIT5Q5 DZNep Lymphoid neoplasm (Cell Line: Mak) [1]
Sunitinib malate + Panobinostat DCWW71N Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Sunitinib malate + Marizomib DC603T4 Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Sunitinib malate + Piperacetazine DCDWTBN Piperacetazine Hepatocellular carcinoma (Cell Line: Huh-7) [1]
Sunitinib malate + RG6046 DC1ZLN7 RG6046 Lymphoid neoplasm (Cell Line: Mak) [1]
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⏷ Show the Full List of 10 DrugCom(s)

References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.