Details of the Drug Combinations

General Information of This Drug (ID: DMO0892)

Drug Name

PF-4708671 DMO0892

Synonyms

PF4708671; PF 4708671

Indication

Disease Entry	ICD 11	Status	REF
Ulcerative colitis	DD71	Clinical trial	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
PF-4708671 + Idarubicin	DCW3CWW	Idarubicin	Glioblastoma? (Cell Line: T98G)	[2]
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References

1	Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). Biochem J. 2010 Oct 15;431(2):245-55.
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.