Details of the Drug Combinations

General Information of This Drug (ID: DMO14SG)

Drug Name
Mebendazole   DMO14SG
Synonyms
Bantenol; Banworm; Besantin; Lomper; MBDZ; Madicure; Mebendan; Mebendazol; Mebendazolum; Mebenoazole; Mebenvet; Mebex; Mebutar; Noverme; Ovitelmin; Pantelmin; Sqworm; Sufil; Surfont; Telmin; Vermicidin; Vermicol; Vermidil; Vermin; Vermirax; Vermox; Verpanyl; Versid; Wormkuur; Abello Farmacia Brand of Mebendazole; Anti Worm; Ardeypharm Brand of Mebendazole; Boots Brand of Mebendazole; Boots Threadworm Treatment; Diba Brand of Mebendazole; Elfar Brand of Mebendazole; Equivurm Plus; Esteve Brand of Mebendazole; Healthypharm Brand of Mebendazole; Janssen Brand of Mebendazole; Leidapharm Brand of Mebendazole; Norgine Brand of Mebendazole; Pfizer Brand of Mebendazole; Pripsen Mebendazole; SSL Brand of Mebendazole; Streger Brand of Mebendazole; Taxandria Brand of Mebendazole; Tedec Meiji Brand of Mebendazole; R 17635; R17635; Anti-Worm; Antiox (TN); Degort's Brand of Mebendazole; Mebendazol [INN-Spanish]; Mebendazole(USAN); Mebendazolum [INN-Latin]; Ovex (TN); Pripsen (TN); R 17,635; R-17635; Vermox (TN); MEBENDAZOLE, 99%; Mebendazole (JAN/USP); Mebendazole (JAN/USP/INN); Mebendazole [USAN:INN:BAN:JAN]; Methyl5-benzoyl benzimidazole-2-carbamate; Methyl 5-benzoyl-2-benzimidazolecarbamate; Methyl 5-benzoyl-2-benzimidazolylcarbamate; N-2 (5-Benzoyl-benzimidazole) carbamate de methyle; N-2 (5-Benzoyl-benzimidazole) carbamate de methyle [French]; Methyl N-(5-benzoyl-2-benzimidazolyl)carbamate; Methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate; Methyl [5-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate; N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle; N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle [French]; Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate; Methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate; Carbamic acid, N-(5-benzoylbenzimidazol-2-yl)-, methyl ester; Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester; Methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate; Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester (9CI); (5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester; (5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester; (5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester; 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester; 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester (8CI); 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester; 5-Benzoyl-2-benzimidazolecarbamic acid, methyl ester
Indication
Disease Entry ICD 11 Status REF
Ascariasis 1F62 Approved [1]
Enterobiasis 1F65 Approved [1]
Helminth infection 1F90.0 Approved [1]
Trichuris trichiura infection 1F6G Approved [1]
Worm infection 1F90.Z Approved [2]
Therapeutic Class
Antinematodal Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

93 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Abexinostat + Mebendazole DCM6EPY Abexinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Acamprosate + Mebendazole DC9417Y Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Arfolitixorin + Mebendazole DCOBP9P Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Mebendazole DCQMX55 Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bafilomycin A1 + Mebendazole DCZ5NSL Bafilomycin A1 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Bardoxolone methyl + Mebendazole DC8B6CJ Bardoxolone methyl Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Bardoxolone methyl + Mebendazole DCEU165 Bardoxolone methyl Primitive neuroectodermal tumor (Cell Line: TC-32) [3]
BIO-300 + Mebendazole DC902K9 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bortezomib + Mebendazole DCVOZ3F Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Mebendazole DCEMXB1 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
CA4P + Mebendazole DCHSO8B CA4P Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Chlormezanone + Mebendazole DC0GCPJ Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Citarinostat + Mebendazole DCNWZRP Citarinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
CPG 52364 + Mebendazole DCPRIX7 CPG 52364 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Cytarabine + Mebendazole DCZIA45 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dasatinib + Mebendazole DC43CDY Dasatinib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
DZNep + Mebendazole DCOH9YM DZNep Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
ETHISTERONE + Mebendazole DCY97ZX ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Everolimus + Mebendazole DCT8IGE Everolimus Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Fomepizole + Mebendazole DC81PXC Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
GSK618334 + Mebendazole DCLG49L GSK618334 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Lenalidomide + Mebendazole DC2S182 Lenalidomide Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Levamisole + Mebendazole DCW1SKV Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
LY2157299 + Mebendazole DC37GAI LY2157299 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Maprotiline + Mebendazole DCNZ2H5 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Aprepitant DCQR284 Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Triiodothyronine DCWZ13V Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Gefitinib DCZP3LW Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Gefitinib DC56O3E Gefitinib Primitive neuroectodermal tumor (Cell Line: TC-32) [3]
Mebendazole + Diethylcarbamazine DC0XSAF Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Buparlisib DCB16UJ Buparlisib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + GDC0941 DCKO7P9 GDC0941 Glioblastoma (Cell Line: JHH-136) [3]
Mebendazole + Ruxolitinib DC2QKEF Ruxolitinib Hodgkin lymphoma (Cell Line: L-1236) [3]
Mebendazole + Trametinib DC95J9G Trametinib Glioblastoma (Cell Line: JHH-136) [3]
Mebendazole + Terazosin DC7VX73 Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Epinephrine DCJCV0D Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + JQ1 DCB3U1E JQ1 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + Panobinostat DC4RFYF Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + Alvespimycin hydrochloride DCJ8RBP Alvespimycin hydrochloride Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + CA4P DCBQVJ6 CA4P Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + CA4P DCHTZ61 CA4P Glioblastoma (Cell Line: JHH-136) [3]
Mebendazole + IT-141 DCB92ZK IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Terameprocol DC1XW6D Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Itraconazole DC847E7 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Chlorzoxazone DCJ1QBH Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Docetaxel DCOH1YN Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + THAPSIGARGIN DC3DDUZ THAPSIGARGIN Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Mebendazole + THAPSIGARGIN DC68PZP THAPSIGARGIN Primitive neuroectodermal tumor (Cell Line: TC-32) [3]
Mebendazole + Mifepristone DCVP2BS Mifepristone Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Mebendazole + Pelitinib DCDXSVB Pelitinib Glioblastoma (Cell Line: JHH-136) [3]
Mebendazole + OSI-027 DC2PX3J OSI-027 Glioblastoma (Cell Line: JHH-136) [3]
Mebendazole + Isoproterenol DCMZYAN Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Imatinib DCYNC0Q Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Methylene blue DCBFD28 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Bardoxolone methyl DC32H0U Bardoxolone methyl Glioblastoma (Cell Line: JHH-136) [3]
Mebendazole + BIIB-021 DCQD76E BIIB-021 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Mebendazole + BMS-754807 DCQBGV6 BMS-754807 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + Brincidofovir DCB3YRW Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + PHA848125 DC9DSYZ PHA848125 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + Hyodeoxycholic acid DCX3GDG Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + PF-562271 DCD2R33 PF-562271 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + Mycophenolic acid DC2Q5NW Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + AZD8330 DCFWPKH AZD8330 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
Mebendazole + Mefloquine DCLDN5P Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Mefloquine DCW09SC Mefloquine Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Mebendazole + Mefloquine DCZ6NYQ Mefloquine Primitive neuroectodermal tumor (Cell Line: TC-32) [3]
Mebendazole + Pizotyline DCTUHPI Pizotyline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Fosfomycin DCF963V Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Estramustine DCQXINI Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Raltegravir DCSL45X Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + GSK2194069 DCX7F6P GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Etomidate DCE8VVN Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Mebendazole DCCG7IG Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Mebendazole DCAMRXC Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
MK-2206 + Mebendazole DCBJVJS MK-2206 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
ONC201 + Mebendazole DCU01NB ONC201 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
OSI-027 + Mebendazole DC507E8 OSI-027 Glioblastoma (Cell Line: JHH-136) [3]
PAC1 + Mebendazole DCKLRIS PAC1 Glioblastoma (Cell Line: JHH-136) [3]
PF-02545920 + Mebendazole DCAUJ1T PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PFI-3 + Mebendazole DCPQPSQ PFI-3 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
PHA-739358 + Mebendazole DC5NOXV PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Piperaquine + Mebendazole DC4T3YC Piperaquine Glioblastoma (Cell Line: JHH-136) [3]
PMID28460551-Compound-2 + Mebendazole DCF4JTE PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PMID28870136-Compound-43 + Mebendazole DC5JAD1 PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
SB-505124 + Mebendazole DCU3RPC SB-505124 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
SGC707 + Mebendazole DCPZNS8 SGC707 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [3]
SNDX-275 + Mebendazole DCP7UXP SNDX-275 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
SNS-032 + Mebendazole DC5QFAF SNS-032 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [3]
Teriflunomide + Mebendazole DC63YRU Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tiagabine + Mebendazole DCMVCS7 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + Mebendazole DCK30NH Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Mebendazole DC9K3GR Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ursodeoxycholic acid + Mebendazole DC3M7BY Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 93 DrugCom(s)
1 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Lenvatinib + Mebendazole DC0FGIQ Lenvatinib Hepatocellular Carcinoma [4]
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References

1 Mebendazole FDA Label
2 Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT04443049) To Study the Effects of Addition of Mebendazole to Lenvatinib in Cirrhotics With Advanced Hepatocellular Carcinoma.