General Information of This Drug (ID: DMO6315)

Drug Name
Vonoprazan   DMO6315
Synonyms TAK-438
Indication
Disease Entry ICD 11 Status REF
Helicobacter infection DA42-DA63 Approved [1]
Gastroesophageal reflux disease DA22.Z Phase 3 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

10 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Clarithromycin + Vonoprazan DC52MW8 Clarithromycin Helicobacter Pylori [3]
Vonoprazan + Amoxicillin DCHMOXE Amoxicillin Helicobacter Pylori Infection [4]
Clarithromycin + Vonoprazan DC23ZIF Clarithromycin Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other [5]
Clarithromycin + Vonoprazan DCK6IOU Clarithromycin Helicobacter Pylori Infection [6]
Clarithromycin + Vonoprazan DCSNZ5N Clarithromycin Treatment Effectiveness [7]
Vonoprazan + Amoxicillin DCMFNTG Amoxicillin Helicobacter Pylori Infection [6]
Berberine + Vonoprazan DCY9GMT Berberine Helicobacter Pylori Infection [8]
Rifabutin + Vonoprazan DC78K1O Rifabutin Helicobacter Pylori Infection [9]
Vonoprazan + Amoxicillin DCI69N4 Amoxicillin Helicobacter Pylori Infection [10]
Vonoprazan + Metronidazole DCY33NS Metronidazole Helicobacter Pylori Infection [11]
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⏷ Show the Full List of 10 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2008
2 ClinicalTrials.gov (NCT02388724) Efficacy and Safety of Oral Once-Daily Vonoprazan (TAK-438) in Patients With Erosive Esophagitis. U.S. National Institutes of Health.
3 ClinicalTrials.gov (NCT04753437) A Study of Vonoprazan in Adults With Helicobacter Pylori
4 ClinicalTrials.gov (NCT05189444) The Evaluation of Triple Therapy With Vonoprazan, Amoxicillin and Bismuth for Eradication of Helicobacter Pylori
5 ClinicalTrials.gov (NCT03219723) Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"
6 ClinicalTrials.gov (NCT04167670) Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection
7 ClinicalTrials.gov (NCT06162949) Vonoprazan for Helicobacter Pylori Eradication in Adolescents
8 ClinicalTrials.gov (NCT05014334) Study on The Efficacy and Safety of Berberine-containing Triple Therapy in Helicobacter Pylori First-Line Eradication
9 ClinicalTrials.gov (NCT05874544) Rescue Therapy for Helicobacter Pylori Infection
10 ClinicalTrials.gov (NCT05419674) Efficacy and Safety of Dual Therapy as First-line Treatment for Hp Infection
11 ClinicalTrials.gov (NCT05726734) Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical Trial