Details of the Drug Combinations

General Information of This Drug (ID: DMPK32V)

Drug Name
BMS-754807   DMPK32V
Synonyms
BMS-754807; 1001350-96-4; BMS 754807; BMS754807; UNII-W9E3353E8J; CHEMBL575448; CHEBI:88339; W9E3353E8J; 1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-prolinamide; W-204348; J-501009; 2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-, (2S)-;2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridin
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

112 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Abexinostat + BMS-754807 DCS2NF4 Abexinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Afatinib + BMS-754807 DCPEH4J Afatinib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Belinostat + BMS-754807 DC284UN Belinostat Embryonal rhabdomyosarcoma (Cell Line: Rh36) [2]
Belinostat + BMS-754807 DCX0LF7 Belinostat Embryonal rhabdomyosarcoma (Cell Line: CTR) [2]
Belinostat + BMS-754807 DCGS75C Belinostat Embryonal rhabdomyosarcoma (Cell Line: RD) [2]
BGJ398 + BMS-754807 DCIKFOR BGJ398 Embryonal rhabdomyosarcoma (Cell Line: Rh36) [2]
BGJ398 + BMS-754807 DCF0T5U BGJ398 Embryonal rhabdomyosarcoma (Cell Line: CTR) [2]
BGJ398 + BMS-754807 DCCYTSA BGJ398 Embryonal rhabdomyosarcoma (Cell Line: RD) [2]
BMS-754807 + Gefitinib DCS4180 Gefitinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + Gefitinib DCBXGK2 Gefitinib Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + Buparlisib DCP69GY Buparlisib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + PD-0325901 DC1H1JS PD-0325901 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + PD-0325901 DCS2CFH PD-0325901 Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + AT13387 DCG9QNG AT13387 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Trametinib DC1JBLT Trametinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + Trametinib DCR02WS Trametinib Embryonal rhabdomyosarcoma (Cell Line: Rh36) [1]
BMS-754807 + Trametinib DC5574T Trametinib Embryonal rhabdomyosarcoma (Cell Line: CTR) [1]
BMS-754807 + Trametinib DCWP86P Trametinib Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
BMS-754807 + JQ1 DCUXPF0 JQ1 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + JQ1 DCYUI3F JQ1 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + JQ1 DCTS3NH JQ1 Embryonal rhabdomyosarcoma (Cell Line: Rh36) [1]
BMS-754807 + JQ1 DCWXF5Y JQ1 Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
BMS-754807 + Carfilzomib DC5JLI3 Carfilzomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + PMID28460551-Compound-2 DC4D1ND PMID28460551-Compound-2 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Panobinostat DCKDGRH Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Panobinostat DCMKC1I Panobinostat Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + Panobinostat DCNJZM6 Panobinostat Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + Ixazomib DCNNSIO Ixazomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + RTB101 DC2HAYL RTB101 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Alvespimycin hydrochloride DCQM0GG Alvespimycin hydrochloride Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Abexinostat DCJ48NO Abexinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + CA4P DC3Z6AN CA4P Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + CUDC-101 DC8T02F CUDC-101 Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + PMID25656651-Compound-5 DCQ8MEU PMID25656651-Compound-5 Embryonal rhabdomyosarcoma (Cell Line: Rh36) [1]
BMS-754807 + PMID25656651-Compound-5 DC3BX78 PMID25656651-Compound-5 Embryonal rhabdomyosarcoma (Cell Line: CTR) [1]
BMS-754807 + PMID25656651-Compound-5 DC50YSE PMID25656651-Compound-5 Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
BMS-754807 + Cantharidin DCR74YS Cantharidin Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + RAF265 DCWVULK RAF265 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + THAPSIGARGIN DCHFFHD THAPSIGARGIN Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + THAPSIGARGIN DC5CYDL THAPSIGARGIN Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + Marizomib DCGXVLA Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Marizomib DCRKX7Y Marizomib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + SNS-032 DCHSYPN SNS-032 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + SNDX-275 DCM4B1F SNDX-275 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + SNDX-275 DCJD5RX SNDX-275 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + GSK618334 DCD8JE3 GSK618334 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + AS602868 DCZH4EO AS602868 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + Tamoxifen DCGYVUN Tamoxifen Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + Tamoxifen DCQQIVU Tamoxifen Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + Idarubicin DCOWVAM Idarubicin Glioblastoma? (Cell Line: T98G) [1]
BMS-754807 + Ciclopirox DCI6I60 Ciclopirox Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + Resminostat DC8LVMU Resminostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + IMD-0354 DCBJ8IK IMD-0354 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + CF102 DCLKY6W CF102 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + BIIB-021 DCGQUXT BIIB-021 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
BMS-754807 + BMS-754807 DCR91SW BMS-754807 Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
BMS-754807 + Citarinostat DCCNT98 Citarinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + PF-562271 DCCI9RO PF-562271 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + PF-562271 DC9Z4S4 PF-562271 Embryonal rhabdomyosarcoma (Cell Line: SMS-CTR) [1]
BMS-754807 + PF-562271 DCRX6HS PF-562271 Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
BMS-754807 + PF-562271 DC2706X PF-562271 Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
BMS-754807 + MK-2206 DC1PXTK MK-2206 Embryonal rhabdomyosarcoma (Cell Line: SMS-CTR) [1]
BMS-754807 + MK-2206 DC1DPUT MK-2206 Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
BMS-754807 + MK-2206 DC441HM MK-2206 Embryonal rhabdomyosarcoma (Cell Line: Rh36) [1]
BMS-754807 + THZ1 DC3OL0T THZ1 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + AZD8330 DC43Z36 AZD8330 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + Vorinostat DC1BFF0 Vorinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
BMS-754807 + CB3304 DCWDJJA CB3304 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
CA4P + BMS-754807 DC26UV6 CA4P Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Ceritinib + BMS-754807 DCIJ9RY Ceritinib Embryonal rhabdomyosarcoma (Cell Line: Rh36) [2]
Citarinostat + BMS-754807 DCNH812 Citarinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Dasatinib + BMS-754807 DCYRJWG Dasatinib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Dasatinib + BMS-754807 DCIDGK1 Dasatinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Dasatinib + BMS-754807 DCY1XB7 Dasatinib Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
Dorsomorphin + BMS-754807 DCLBIKJ Dorsomorphin Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Dorsomorphin + BMS-754807 DC5QY71 Dorsomorphin Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
Doxorubicin + BMS-754807 DCBBM2L Doxorubicin Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Everolimus + BMS-754807 DCL0II0 Everolimus Embryonal rhabdomyosarcoma (Cell Line: Rh36) [1]
Everolimus + BMS-754807 DC3IED4 Everolimus Embryonal rhabdomyosarcoma (Cell Line: CTR) [1]
Everolimus + BMS-754807 DCTADUS Everolimus Embryonal rhabdomyosarcoma (Cell Line: RD) [1]
Flavopiridol + BMS-754807 DCV0VZG Flavopiridol Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Fostamatinib + BMS-754807 DC2ZSP5 Fostamatinib Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
GSK2126458 + BMS-754807 DCCUU9L GSK2126458 Embryonal rhabdomyosarcoma (Cell Line: Rh36) [2]
GSK2126458 + BMS-754807 DCSW4ID GSK2126458 Embryonal rhabdomyosarcoma (Cell Line: CTR) [2]
GSK2126458 + BMS-754807 DC7XIF3 GSK2126458 Embryonal rhabdomyosarcoma (Cell Line: RD) [2]
IT-141 + BMS-754807 DCIYWBI IT-141 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Marimastat + BMS-754807 DCXHQ69 Marimastat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Mebendazole + BMS-754807 DCQBGV6 Mebendazole Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Mitapivat + BMS-754807 DCD4B0T Mitapivat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
MK-1775 + BMS-754807 DC7HRPI MK-1775 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
MK-2206 + BMS-754807 DCYH6XO MK-2206 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
MLN8237 + BMS-754807 DC819RJ MLN8237 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
ONC201 + BMS-754807 DCGVQZG ONC201 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Palbociclib + BMS-754807 DC29FGP Palbociclib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
PD-0325901 + BMS-754807 DC9VZXK PD-0325901 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
PHA848125 + BMS-754807 DCHMSDZ PHA848125 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Raloxifene + BMS-754807 DCF05DZ Raloxifene Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Raloxifene + BMS-754807 DC9EWAV Raloxifene Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
Ribavirin-TP + BMS-754807 DC1839J Ribavirin-TP Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
RTB101 + BMS-754807 DCCU8JN RTB101 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
RTB101 + BMS-754807 DC4NMG7 RTB101 Primitive neuroectodermal tumor (Cell Line: TC-32) [1]
SCH 727965 + BMS-754807 DC9SBLG SCH 727965 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
SCH772984 + BMS-754807 DCGOX4N SCH772984 Embryonal rhabdomyosarcoma (Cell Line: Rh36) [2]
SCH772984 + BMS-754807 DCPNVDS SCH772984 Embryonal rhabdomyosarcoma (Cell Line: CTR) [2]
SCH772984 + BMS-754807 DCJDGPY SCH772984 Embryonal rhabdomyosarcoma (Cell Line: RD) [2]
Teriflunomide + BMS-754807 DCIP3M8 Teriflunomide Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
THAPSIGARGIN + BMS-754807 DC5E51X THAPSIGARGIN Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
THZ1 + BMS-754807 DCN6XA4 THZ1 Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Tosyl-l-arginine methyl ester + BMS-754807 DCVMFRD Tosyl-l-arginine methyl ester Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Trametinib + BMS-754807 DC0T4P3 Trametinib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
Venglustat + BMS-754807 DCBZ3WS Venglustat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
Vincristine + BMS-754807 DCGU2LS Vincristine Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
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References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
2 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.