Details of the Drug Combinations

General Information of This Drug (ID: DMR6QH0)

Drug Name

Venlafaxine DMR6QH0

Synonyms

Efectin; Elafax; Venlafaxina; VenlafaxineXR; Venlafaxinum; Venlafaxine ER; Wy 45030; Efectin (TN); Venlafaxina [INN-Spanish];Venlafaxine (Effexor); Venlafaxine (INN); Venlafaxine [BAN:INN]; Venlafaxine [INN:BAN]; Venlafaxinum [INN-Latin]; N,N-dimethyl-2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethylamine; 1-[(1R)-2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol; 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol; 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol; 1-[2-dimethylamino-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol; 1-{2-(dimethylamino)-1-[4-(methyloxy)phenyl]ethyl}cyclohexanol

Indication

Disease Entry	ICD 11	Status	REF
Anxiety disorder	6B00-6B0Z	Approved	[1]
Depression	6A70-6A7Z	Approved	[2]
Major depressive disorder	6A70.3	Approved	[1]
Panic disorder	6B01	Approved	[1]
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Therapeutic Class

Antidepressants

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

5 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Buprenorphine + Venlafaxine	DCR41AO	Buprenorphine	Major Depressive Disorder	[3]
Eszopiclone + Venlafaxine	DCH0JYQ	Eszopiclone	Major Depressive Disorder	[4]
Lithium Carbonate + Venlafaxine	DC1SKJ7	Lithium Carbonate	Depressive Disorder, Major	[5]
Sertraline + Venlafaxine	DCO3IIW	Sertraline	Depression	[6]
Venlafaxine + Fingolimod	DCH97QT	Fingolimod	Depression	[7]
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References

1	Venlafaxine FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7321).
3	ClinicalTrials.gov (NCT02263248) Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine
4	ClinicalTrials.gov (NCT00435279) A Study of Eszopiclone Co-administered With Venlafaxine in Subjects With Major Depressive Disorder and Insomnia
5	ClinicalTrials.gov (NCT00627887) Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression
6	ClinicalTrials.gov (NCT00043550) Treatments for Depression: Drug Versus Psychotherapy
7	ClinicalTrials.gov (NCT01436643) Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With Depression