Details of the Drug Combinations

General Information of This Drug (ID: DMRWLB2)

Drug Name
Fluticasone propionate   DMRWLB2
Synonyms
FLUTICASONE PROPIONATE; Flovent; Cutivate; Flixotide; Flonase; Flixonase; Flovent HFA; Flunase; Flutide; Fluspiral; Flusonal; atemur; Flutivate; Fluinol; Axotide; Asmatil; Brethal; Flovent Diskus 50; Flixotide Disks; Flixotide Disk; Flovent Diskus; Flovent Diskus 100; Flovent Diskus 250; Flixotide Inhaler; Trialona; Rinosone; Inalacor; Cultivate; Ubizol; Zoflut; Flixonase Nasal Spray; Flonase Aq; Fluticasonpropionat Allen; Fluticasone (propionate); UNII-O2GMZ0LF5W; CCI-18781; CCI 18781; MFCD00866007; O2GMZ0LF5W
Indication
Disease Entry ICD 11 Status REF
Allergic asthma CA23.0 Approved [1]
Allergic rhinitis CA08.0 Approved [1]
Bronchiolitis N.A. Approved [1]
Exanthem N.A. Approved [1]
Granuloma annulare N.A. Approved [1]
Intrinsic asthma N.A. Approved [1]
Primary cutaneous T-cell lymphoma N.A. Approved [1]
Pulmonary emphysema CA21.Z Approved [1]
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Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

4 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Fluticasone propionate + Idarubicin DCWMQ51 Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Fluticasone propionate + Ruxolitinib DCEOXXO Ruxolitinib Hodgkin lymphoma (Cell Line: L-1236) [3]
Miconazole + Fluticasone propionate DCS3CKB Miconazole DD2 (Cell Line: DD2) [2]
Miconazole + Fluticasone propionate DCRTK86 Miconazole Hepatoblastoma (Cell Line: HB3) [3]
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2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Fluticasone propionate + GW685698X DCW4LI3 GW685698X Asthma [4]
Salmeterol + Fluticasone propionate DCYZFC5 Salmeterol Allergic Asthma [5]
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1 Approved Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Salmeterol + Fluticasone propionate DCU6QC9 Salmeterol Asthma [6]
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References

1 Fluticasone propionate FDA Label
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
4 Fluticasone furoate/fluticasone propionate - different drugs with different properties. Clin Respir J. 2011 July; 5(3): 183-184.
5 ClinicalTrials.gov (NCT00214019) The Effect of Salmeterol on Eosinophil (EOS) Function
6 UniProt: the universal protein knowledgebase. Nucleic Acids Res. 2017 Jan 4;45(D1):D158-D169. (ID: O95477)