Details of the Drug Combinations

General Information of This Drug (ID: DMSA4B3)

Drug Name
Desoxycorticosterone Pivalate   DMSA4B3
Synonyms
DOCP; DTMA; Cortexone M; Deoxycorticosterone pivalate; Deoxycorticosterone trimethylacetate; Deoxycortolone Pivalate; Deoxycortone pivalate; Deoxycortone trimethylacetate; Desoxycorticosterone trimethylacetate; Desoxycortone pivalate; Percorten M; Percorten Pivalate; Desoxycorticosterone pivalate (USP); Neodin-depositum; Percorten (TN); Corticosterone, deoxy-, pivalate (6CI,7CI); [2-(10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] 2,2-dimethylpropanoate; 11-Deoxycorticosterone pivalate; 11-Deoxycorticosterone, pivalate; 11-Deoxycorticosterone, pivalate (8CI); 21-(2,2-Dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione; 3,20-dioxopregn-4-en-21-yl 2,2-dimethylpropanoate
Indication
Disease Entry ICD 11 Status REF
Addison disease 5A74.0 Approved [1]
Therapeutic Class
Antiaddison Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

51 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Desoxycorticosterone pivalate DCWGHFQ Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Allopurinol + Desoxycorticosterone pivalate DCF6PD8 Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cerivastatin + Desoxycorticosterone pivalate DC1WTLY Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorzoxazone + Desoxycorticosterone pivalate DCOU829 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Diethylcarbamazine DCKWVE3 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Epinephrine DCK1N3P Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + PMID28460551-Compound-2 DC1QJUV PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Vinblastine DC9ST3Z Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Anamorelin DC2APXH Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Triapine DCZTAY0 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Rifampin DCCN2PS Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + IT-141 DCD158X IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Methylergonovine DCY7HQO Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Itraconazole DCLEMOM Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Memantine DCGTI8H Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Docetaxel DCPH3KU Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Galantamine DCPK12O Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + PHA-739358 DC67P5L PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Procarbazine DCCA86A Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + PFK-158 DCFTGK7 PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Arfolitixorin DCBUFA4 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Niclosamide DCCKF98 Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + PF-02545920 DCIXRCD PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Tiagabine DCFVTBN Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Diazoxide DCATR1Y Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Idarubicin DC1R8ZS Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Probenecid DCJDXLO Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Abacavir DCHCPFZ Abacavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Acetohexamide DCR2OGQ Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Leflunomide DCNYCFZ Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Chlorambucil DCSOJVZ Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Hyodeoxycholic acid DCJHCIH Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Mycophenolic acid DCCIQ8I Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Desoxycorticosterone pivalate + Cytarabine DCUN1KC Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dichlorphenamide + Desoxycorticosterone pivalate DCNRYUY Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dopamine + Desoxycorticosterone pivalate DC2RHEK Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Desoxycorticosterone pivalate DC0ZS1T Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Desoxycorticosterone pivalate DC7FIQJ Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Isosorbide dinitrate + Desoxycorticosterone pivalate DCOQ5NA Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Desoxycorticosterone pivalate DCDAAPR Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Desoxycorticosterone pivalate DC86HGZ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + Desoxycorticosterone pivalate DCGD429 Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methotrexate + Desoxycorticosterone pivalate DCX9M37 Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Desoxycorticosterone pivalate DCQH076 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentamidine + Desoxycorticosterone pivalate DCR0FND Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sertraline + Desoxycorticosterone pivalate DCTK4WE Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sitagliptin + Desoxycorticosterone pivalate DCRPA7A Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sulfapyridine + Desoxycorticosterone pivalate DCZJXOH Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terazosin + Desoxycorticosterone pivalate DC39Z6I Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tropisetron + Desoxycorticosterone pivalate DCKR6JE Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Desoxycorticosterone pivalate DC9T3ZW Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 51 DrugCom(s)

References

1 Drug information of Desoxycorticosterone Pivalate, 2008. eduDrugs.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.