Details of the Drug Combinations

General Information of This Drug (ID: DMTWUXR)

Drug Name
Chlormezanone   DMTWUXR
Synonyms
Alinam; Banabin; Bisina; Chlomedinon; Chlormethazanone; Chlormethazone; Chlormezanon; Chlormezanona; Chlormezanonum; Clorilax; Clormetazanone; Clormetazon; Clormezanona; Clormezanone; Dichloromethazanone; Dichloromezanone; Lobak; Miorilax; Muskel; Myolespen; Phenarol; Rexan; Rilansyl; Rilaquil; Rilasol; Rilassol; Rilax; Rillasol; Supotran; Suprotan; Tanafol; Trancopal; Trancote; Tranrilax; Transanate; Clormezanone [DCIT]; WIN 4692; Banabil-sintyal; Banabin-sintyal; Banabin-syntyal; C-192; Chlormezanonum [INN-Latin]; Clormezanona [INN-Spanish]; Dl-Chlormezanone; Mio-sed; Muskel-Trancopal; TRANCOPAL (TN); Trancopal (TN); Chlormezanone (JAN/INN); Chlormezanone [BAN:INN:JAN]; Chlormezanone [INN:BAN:JAN]; (+-)-Chlormezanone; 2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide; 2-(4-Chlorophenyl)-3-methyl-4-metathiazanone-1,1-dioxide; 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H,1,3-thiazin-4-one 1,1-Dioxide; 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide; 2-(4-Chlorphenyl)-3-methyl-4-metathiazanon-1,1-dioxid; 2-(4-chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one; 2-(p-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide; 2-(p-Chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide; 2-(para-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one, 1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(4-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(4-chlorophenyl)tetrahydro-3-methyl-1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(p-chlorophenyl)tetrahydro-3-methyl-, 1,1,-dioxide; 4H-1,3-Thiazin-4-one, 2-(p-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide; 4H-1,3-Thiazin-4-one, 2-(p-chlorophenyl)tetrahydro-3-methyl-1,1-dioxide; 4H-1,3-Thiazin-4-one, tetrahydro-2-(p-chlorophenyl)-3-methyl-, 1,1-dioxide
Indication
Disease Entry ICD 11 Status REF
Anxiety disorder 6B00-6B0Z Approved [1]
Therapeutic Class
Analgesics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

59 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acetohydroxamic Acid + Chlormezanone DCVQKKV Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Auranofin + Chlormezanone DCZ3GC6 Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Chlormezanone DCXEDNT Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Aprepitant DC0AFQ4 Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Gefitinib DCKG3DM Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Paromomycin DCDTNOT Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Dantrolene DCSHI1U Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Lumefantrine DC9JGI4 Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Tindamax DCG90GK Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + PMID28460551-Compound-2 DCWF7KV PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Mephenytoin DCGQGBW Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Fomepizole DCHDL1G Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Triapine DCPDJ8J Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Everolimus DCTI0A9 Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + 10-hydroxycamptothecin DC9OMGB 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + IT-141 DCCOYXH IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Metyrosine DCVM1K5 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Emetine DCERMT7 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Pazopanib DCHPYOR Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + PHA-739358 DCSP84J PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Arfolitixorin DCJ4N3F Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Niclosamide DCZKB1G Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + PF-02545920 DCW6TA7 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Tiagabine DCUAMRH Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Diazoxide DC2RRJY Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Fenoprofen DC4V3VQ Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Imatinib DCNNDX2 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Methylene blue DCUTCH4 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Mebendazole DC0GCPJ Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Artemisinin DCPLHRF Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Olanzapine DCEX63Q Olanzapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Maprotiline DCKMQWK Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Leflunomide DCLZD6O Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Brincidofovir DCQM7BE Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Endoxifen DCBN4XU Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Mycophenolic acid DCCG3QL Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Mefloquine DC3PT5N Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Lacosamide DCPHJWK Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Doxorubicin DCJTXX4 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Rufinamide DC8X9PZ Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Cytarabine DCZ5D27 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilastatin + Chlormezanone DCVFZ71 Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diethylcarbamazine + Chlormezanone DCOXHRV Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Docetaxel + Chlormezanone DCJH6FR Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Efavirenz + Chlormezanone DC0OW8R Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Isoproterenol + Chlormezanone DCPYQKA Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Kanamycin + Chlormezanone DC4G0O7 Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lacosamide + Chlormezanone DC8Y1UZ Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Chlormezanone DCPG53K Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Chlormezanone DC8V2ZP Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Chlormezanone DC52U0V Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oseltamivir + Chlormezanone DCWQ257 Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oxandrolone + Chlormezanone DCY9GSH Oxandrolone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentamidine + Chlormezanone DC1YE6J Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Phensuximide + Chlormezanone DCRI83L Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Procarbazine + Chlormezanone DCYXYW2 Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trihexyphenidyl + Chlormezanone DCLTSNN Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + Chlormezanone DCK3KA9 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vinblastine + Chlormezanone DCUDH0C Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 59 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7323).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.