Details of the Drug Combinations

General Information of This Drug (ID: DMU7YEL)

• Drug Name: Sufentanil (DMU7YEL)
• Synonyms: Chronogesic; Sufentanilum; Sufentanyl; Sulfentanil; Sulfentanyl; R 30730; R-30730; Sufenta (TN); Sufentanilum [INN-Latin]; Sufentil (TN); Sufentanil (USAN/INN); Sufentanil [USAN:BAN:INN]; N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide; N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenylpropanamide; N-{4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide; N-{4-[(methyloxy)methyl]-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide; N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide

Indication

Analgesia; ICD 11: MB40.8; Status: Approved [1]

• Therapeutic Class: Anesthetics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

12 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Levobupivacaine + Sufentanil	DCAGNA0	Levobupivacaine	Pregnancy	[2]
Lidocaine + Sufentanil	DC4WQ21	Lidocaine	Bronchoscopy	[3]
Morphine + Sufentanil	DCU1UMB	Morphine	Post Operative Pain Management	[4]
Morphine + Sufentanil	DC18MJ1	Morphine	Analgesia	[5]
Propofol + Sufentanil	DCC6E9S	Propofol	Hemodynamic Instability	[6]
Ropivacaine + Sufentanil	DCJKKHM	Ropivacaine	Labor Analgesia	[7]
Sufentanil + Sevoflurane	DC2OMFC	Sevoflurane	Ischemic Heart Disease	[8]
Ketamine + Sufentanil	DC8FXUH	Ketamine	Pain	[9]
Ondansetron + Sufentanil	DC9HM2A	Ondansetron	Trigeminal Neuralgia	[10]
Propofol + Sufentanil	DCYUZ6V	Propofol	Postoperative; Dysfunction Following Cardiac Surgery	[11]
Ropivacaine + Sufentanil	DCJU96D	Ropivacaine	Pain	[12]
Sufentanil + Midazolam	DCRJODP	Midazolam	Sufentanil	[13]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] ClinicalTrials.gov (NCT01856166) PIEB-PCEA Versus CEI-PCEA for Labor Analgesia in Nulliparous
• [3] ClinicalTrials.gov (NCT03738137) Narcotrend Versus Bispectral Index Monitoring During Sufentanil-Midazolam Anesthesia for Bronchoscopy
• [4] ClinicalTrials.gov (NCT01917045) Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia
• [5] ClinicalTrials.gov (NCT05042817) Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
• [6] ClinicalTrials.gov (NCT05423951) Effect of Remimazolam and Propofol on Hemodynamic Stability During Anesthesia Induction in OPCAB Patients
• [7] ClinicalTrials.gov (NCT02873091) Comparison of Programmed Intermittent Epidural Bolus With Continuous Epidural Infusion for Labor Epidural Analgesia
• [8] ClinicalTrials.gov (NCT02499445) Myocardial Injury in Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimens in OPCAB Surgery
• [9] ClinicalTrials.gov (NCT05508594) Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001
• [10] ClinicalTrials.gov (NCT03152955) Postoperative Analgesia in Patients With Microvascular Decompression
• [11] ClinicalTrials.gov (NCT02756598) Stress, Anxiety and Type A Personality and Analgesics
• [12] ClinicalTrials.gov (NCT02036242) Sole Local Anesthetic Versus Opioid Plus Local Anesthesia in Epidural Labor Analgesia
• [13] ClinicalTrials.gov (NCT03901716) Comparison of Sufentanil, Fentanyl and Remifentanil in Combination With Midazolam During Bronchoscopy Under Conscious Sedation