Details of the Drug Combinations

General Information of This Drug (ID: DMUFIO9)

Drug Name
M102   DMUFIO9
Indication
Disease Entry ICD 11 Status REF
Amyotrophic lateral sclerosis 8B60.0 Preclinical [1]

List of Combinatorial Drugs (CBD) Containing This Drug

4 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
M102 + Colchicine DCB91BI Colchicine Hyperuricemia [2]
Allopurinol + M102 DC3S2QP Allopurinol Gout [3]
Febuxostat + M102 DC0WGVW Febuxostat Gout [4]
Febuxostat + M102 DCGZRKA Febuxostat Hyperuricemia [5]
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References

1 Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases. Nat Rev Drug Discov. 2019 Apr;18(4):295-317.
2 ClinicalTrials.gov (NCT01336686) Safety and Efficacy Study of MBX-102 in Treatment of Hyperuricemia in Patients With Gout
3 ClinicalTrials.gov (NCT01399008) Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients
4 ClinicalTrials.gov (NCT02252835) Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With Gout
5 ClinicalTrials.gov (NCT01416402) Open Label Safety/Efficacy Study of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Gout Patients