Details of the Drug Combinations

General Information of This Drug (ID: DMUSLW3)

Drug Name

Carbetocin DMUSLW3

Synonyms

Carbetocino [INN-Spanish]; Carbetocinum [INN-Latin]; Duratocin (TN); 1-Buttersaeure-2-(3-(4-methoxyphenyl)-L-alanin)oxytocin; 1-{[(3r,6s,9s,12s,15s)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2s)-butan-2-yl]-15-(4-hydroxybenzyl)-16-methyl-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacycloicosan-3-yl]carbonyl}-l-prolyl-l-leucylglycinamide

Indication

Disease Entry	ICD 11	Status	REF
Postpartum haemorrhage	JA43	Approved	[1]
------------------------------------------------------------------------------------

Therapeutic Class

Antitocolytic Agents

Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Oxytocin + Carbetocin	DCSPUVW	Oxytocin	Postpartum Hemorrhage	[2]
Oxytocin + Carbetocin	DC0F4ZF	Oxytocin	Postpartum Hemorrhage	[3]
Oxytocin + Carbetocin	DC0ABT2	Oxytocin	CARBETOCIN FOR PREVENTION OF PLACENTAL RETAINED	[4]
------------------------------------------------------------------------------------

References

1	Clinical Textbook of Dental Hygiene and Therapy. 2006, P237. By Robert Ireland.
2	ClinicalTrials.gov (NCT06285409) Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
3	ClinicalTrials.gov (NCT01689298) Carbetocin vs. Oxytocin: In-vitro Myometrial Contractions With and Without Oxytocin Pre-treatment
4	ClinicalTrials.gov (NCT01827124) Randomized Clinical Trial for Comparison Of Intravenous Carbeitocin Versus Oxytocin In Management Of Placental Delivery In Second Trimester Interruption