General Information of This Drug (ID: DMW34B1)

Drug Name
Motixafortide   DMW34B1
Synonyms BL-8040
Indication
Disease Entry ICD 11 Status REF
Multiple myeloma 2A83 Approved [1]
Acute myeloid leukaemia 2A60 Phase 2 [2]
Myelodysplastic syndrome 2A37 Phase 2 [3]
Pancreatic cancer 2C10 Phase 2 [3]
Drug Type
Peptide
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
BL-8040 + Cytarabine DCCFUEC Cytarabine Acute Myeloid Leukemia [4]
Nelarabine + BL-8040 DCJXZE3 Nelarabine T-Acute Lymphoblastic Leukemia [5]
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References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 217159
2 ClinicalTrials.gov (NCT02502968) BL-8040 Addition to Consolidation Therapy in AML Patients.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 ClinicalTrials.gov (NCT01838395) Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients
5 ClinicalTrials.gov (NCT02763384) BL-8040 and Nelarabine for Relapsed or Refractory T-Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma