Details of the Drug Combinations

General Information of This Drug (ID: DMX302C)

Drug Name

BMS-690514 DMX302C

Synonyms

BMS 690514; BMS690514

Indication

Disease Entry	ICD 11	Status	REF
Chronic pain	MG30	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
BMS-690514 + Panobinostat	DC8Q4KC	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[2]
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1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Letrozole + BMS-690514	DCBE6FO	Letrozole	Breast Cancer	[3]
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References

1	A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. Cancer Res. 2007 Jul 1;67(13):6253-62.
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3	ClinicalTrials.gov (NCT01068704) Efficacy and Safety of BMS-690514 in Combination With Letrozole to Treat Metastatic Breast Cancer