Details of the Drug Combinations

General Information of This Drug (ID: DMX4GND)

• Drug Name: Meperidine (DMX4GND)
• Synonyms: Demarol; Demerol; Dolcontral; Dolosal; Dolsin; Isonipecain; Isonipecaine; Lidol; Lydol; Meperidol; Nemerol; Pethanol; Pethidin; Pethidine; Pethidineter; Pethidinum; Petidina; Petydyna; Phetidine; Piperosal; Pipersal; Meperidine solution; Methyl phenylpiperidine carbonic acid ethyl ester; Operidine EPJ I; Pethidine DBL; Petydyna [Polish]; Demerol (TN); Operidine EPJ-I; Pethidine (INN); Pethidine DBL (TN); Pethidinum [INN-Latin]; Petidina [INN-Spanish]; Ethyl 1-methyl-4-phenylisonipecotate; Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate; N-Methyl-4-phenyl-4-carbethoxypiperidine; Isonipecotic acid, 1-methyl-4-phenyl-, ethyl ester; YIsonipecotic acid, 1-methyl-4-phenyl-, ethyl ester (8CI); 1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester; 1-Methyl-4-phenyl-piperidin-4-carbon-saeure-aethylester; 1-Methyl-4-phenyl-piperidin-4-carbon-saeure-aethylester [German]; 1-Methyl-4-phenylisonipecotic acid, ethyl ester;1-Methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester; 4-Carbethoxy-1-methyl-4-phenylpiperidine; 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester

Indication

Pain; ICD 11: MG30-MG3Z; Status: Approved [1]

• Therapeutic Class: Anesthetics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

7 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Acetaminophen + Meperidine	DCQ30F7	Acetaminophen	Labor Pain	[2]
Meperidine + Midazolam	DCUPDYO	Midazolam	Disorders of Gallbladder, Biliary Tract and Pancrease	[3]
Propofol + Meperidine	DCVWGZ1	Propofol	Disorders of Gallbladder, Biliary Tract and Pancrease	[3]
Buspirone + Meperidine	DC72YHX	Buspirone	Acute Ischemic Stroke	[4]
Diazepam + Meperidine	DC7RRQK	Diazepam	Infertility	[5]
Fentanyl + Meperidine	DCFYN7L	Fentanyl	Pain	[6]
Hydroxyzine + Meperidine	DCHANHN	Hydroxyzine	Dental Caries in Children	[7]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] ClinicalTrials.gov (NCT05499234) Epidural Tap in Labor Analgesia FOR LABOR ANALGESIA
• [3] ClinicalTrials.gov (NCT01709422) Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.
• [4] ClinicalTrials.gov (NCT01833312) Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke
• [5] ClinicalTrials.gov (NCT02494180) A Non-inferiority Trial on Pain Relief During Oocyte Retrieval
• [6] ClinicalTrials.gov (NCT02684942) Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy
• [7] ClinicalTrials.gov (NCT04068948) Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years