Details of the Drug Combinations

General Information of This Drug (ID: DMX7BM4)

Drug Name

Efaproxyn DMX7BM4

Synonyms

Efaproxiral; RSR13

Indication

Disease Entry	ICD 11	Status	REF
Lung cancer	2C25.0	Phase 3	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

13 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Efaproxyn + Ombrabulin	DCMW0RW	Ombrabulin	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + AZD8055	DC4VVI5	AZD8055	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + Steroid derivative 1	DC146N0	Steroid derivative 1	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + AT7519	DC4L9QL	AT7519	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + OSI-906	DCQEXUW	OSI-906	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + Pelitinib	DCGEQK7	Pelitinib	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + ABT-263	DCICHEL	ABT-263	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + Tivantinib	DC7YEBC	Tivantinib	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + Bardoxolone methyl	DCUK7WN	Bardoxolone methyl	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + (-)-englerin A	DCHSBUX	(-)-englerin A	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + Lestaurtinib	DC5M4XU	Lestaurtinib	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + AXL-1717	DCEHLB0	AXL-1717	Ewing sarcoma (Cell Line: TC-71)	[2]
Efaproxyn + LY2874455	DC37QNW	LY2874455	Ewing sarcoma (Cell Line: TC-71)	[2]
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⏷ Show the Full List of 13 DrugCom(s)

References

1	ClinicalTrials.gov (NCT00083304) Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer. U.S. National Institutes of Health.
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.