Details of the Drug Combinations

General Information of This Drug (ID: DMXLKHV)

• Drug Name: Oxycodone (DMXLKHV)

Indication

Osteoarthritis; ICD 11: FA00-FA05; Status: Approved [1]; Pain; ICD 11: MG30-MG3Z; Status: Approved [2]; Back pain; ICD 11: ME84.Z; Status: Phase 3 [3]

• Therapeutic Class: Analgesics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

17 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Aprepitant + Oxycodone	DCJ12PH	Aprepitant	Narcotic Abuse	[4]
Fentanyl + Oxycodone	DCF2YHO	Fentanyl	Pain, Postoperative	[5]
Fentanyl + Oxycodone	DCU1U36	Fentanyl	Coughing Responses at Tracheal Extubation	[6]
Ibuprofen + Oxycodone	DCYW9RB	Ibuprofen	Opioid Use, Unspecified	[7]
Ketorolac + Oxycodone	DC78RZ0	Ketorolac	Arthrodesis	[8]
Naloxone + Oxycodone	DCGMJ03	Naloxone	Postoperative Pain	[9]
Oxycodone + Lansoprazole	DC2UGBT	Lansoprazole	Pain, Fracture, Sprain	[10]
Oxycodone + Remifentanil	DC5EYQY	Remifentanil	Opioid Use Disorder	[11]
Pregabalin + Oxycodone	DCBT4CD	Pregabalin	Cancer	[12]
Risperidone + Oxycodone	DCD1JKC	Risperidone	Addiction	[13]
Tramadol + Oxycodone	DC69S9M	Tramadol	Osteo Arthritis Knee	[14]
Ziprasidone + Oxycodone	DCHXEDU	Ziprasidone	Addiction	[13]
Acetaminophen + Oxycodone	DCDQNQQ	Acetaminophen	Tonsillectomy	[15]
Ketamine + Oxycodone	DCQOZJW	Ketamine	Acute Pain	[16]
Acetaminophen + Oxycodone	DCGCF6W	Acetaminophen	Pain, Postoperative	[17]
Acetaminophen + Oxycodone	DCOTLR1	Acetaminophen	Post Operative Pain Control	[18]
Ibuprofen + Oxycodone	DCAPBZY	Ibuprofen	Abortion Second Trimester	[19]

References

• [1] Oxycodone FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7093).
• [3] ClinicalTrials.gov (NCT01427283) A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain. U.S. National Institutes of Health.
• [4] ClinicalTrials.gov (NCT00999544) Aprepitant Effects on Oxycodone Response
• [5] ClinicalTrials.gov (NCT03529201) QLB After Nephrectomy
• [6] ClinicalTrials.gov (NCT03204045) Comparison of the Effects of Oxycodone Versus Fentanyl on Airway Reflex to Tracheal Extubation and Postoperative Pain
• [7] ClinicalTrials.gov (NCT03959969) Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery
• [8] ClinicalTrials.gov (NCT05054868) Ketorolac vs Oxycodone for Great Toe Arthrodesis
• [9] ClinicalTrials.gov (NCT01109511) A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy
• [10] ClinicalTrials.gov (NCT00685295) Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain
• [11] ClinicalTrials.gov (NCT03958474) Neurobehavioral Mechanisms of Choice in Opioid Use Disorder
• [12] ClinicalTrials.gov (NCT00637975) Oxycodone and Pregabalin for the Treatment of Oncological Neuropathic Pain
• [13] ClinicalTrials.gov (NCT04587115) Reducing the Abuse Liability of Prescription Opioids
• [14] ClinicalTrials.gov (NCT04003350) The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee Arthroplasty
• [15] ClinicalTrials.gov (NCT02934191) Celecoxib After Tonsillectomy
• [16] ClinicalTrials.gov (NCT02541396) A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing Bunionectomy
• [17] ClinicalTrials.gov (NCT05154682) Pain Management After Surgery
• [18] ClinicalTrials.gov (NCT02160301) Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients
• [19] ClinicalTrials.gov (NCT03545893) Overnight Pain Treatment Investigating Opioids vs. Nonopioids