Details of the Drug Combinations

General Information of This Drug (ID: DMYN59P)

Drug Name

Vildagliptin DMYN59P

Synonyms

Equa; Galvu; Galvus; Jalra; Xiliarx; Galvus (TN); Vidagliptin (see Vildagliptin); Vildagliptin (JAN/USAN/INN); (2S)-(((3-hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile; (2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile; 1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile; 2-Pyrrolidinecarbonitrile, 1-[[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-(9CI)

Indication

Disease Entry	ICD 11	Status	REF
Type-2 diabetes	5A11	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

6 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Escitalopram + Vildagliptin	DCPLTNE	Escitalopram	Major Depressive Disorder	[2]
Glimepiride + Vildagliptin	DC87J1A	Glimepiride	Diabetes Mellitus, Type 2	[3]
Metformin + Vildagliptin	DCULQ98	Metformin	Type-2 diabetes	[4]
Captopril + Vildagliptin	DCI96DN	Captopril	Metabolic Syndrome	[5]
Dapagliflozin + Vildagliptin	DCRBWEF	Dapagliflozin	Type 2 Diabetes	[6]
Metformin + Vildagliptin	DCKZ2K3	Metformin	Coronary Artery Disease	[7]
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⏷ Show the Full List of 6 DrugCom(s)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6310).
2	ClinicalTrials.gov (NCT04410341) The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients
3	ClinicalTrials.gov (NCT00099944) Efficacy and Safety of Vildagliptin in Combination With Glimepiride in Patients With Type 2 Diabetes
4	ClinicalTrials.gov (NCT01518101) Vildagliptin Veresus Liraglutide - Patient Preference After Receiving Both Medications. U.S. National Institutes of Health.
5	ClinicalTrials.gov (NCT04485845) Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression
6	ClinicalTrials.gov (NCT02475070) Vildagliptin Versus Dapagliflozin on Glucagon
7	ClinicalTrials.gov (NCT03693560) Effect of Adding Vildagliptin vs Glimepiride to Metformin on Inflammation's Markers in Type-2 Diabetic Patients With CAD