Details of the Drug Formulations

General Information of Drug (ID: DM3BH1Y)

Drug Name
Lapatinib Drug Info
Synonyms
FMM; Tycerb; Lapatinib Ditosylate; Lapatinib [INN]; Lapatinib tosilate hydrate; GSK 572016; GSK572016; GW 572016; GW 572016X; GW572016; Lapatinib (INN); Tykerb (TN); Lapatinib, Tykerb, GW572016; N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine; N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE; N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-((2-methylsulfonylethylamino)methyl)-2-furyl)quinazolin-4-amine; N-(3-Chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furanyl]-4-quinazolinamine; 4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline; Lapatinib (ERBB2 inhibitor)
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Approved [1]
Gastroesophageal junction adenocarcinoma 2B71 Approved [2]
Melanoma 2C30 Approved [2]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
208908
ChEBI ID
CHEBI:49603
CAS Number
231277-92-2
TTD ID
D08CDI
VARIDT ID
DR00120
INTEDE ID
DR0917
ACDINA ID
D00351

Full List of Drug Formulations Containing This Drug

Lapatinib 250 mg tablet
Company Formulation ID FDA Description
GlaxoSmithKline; Novartis Pharmaceuticals Corporation F11341 Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato
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Lapatinib Ditosylate eq 250mg base tablet
Company Formulation ID FDA Description
Novartis F23348 Magnesium Stearate; Microcrystalline Cellulose; Povidone; Sodium Starch Glycolate; Fd&C Yellow No. 6/Sunset Yellow Fcf Aluminum Lake; Hypromellose; Macrogol/Peg 400; Polysorbate 80; Titanium Dioxide
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5692).
2 Lapatinib FDA Label